NCCN Guidelines™ and NCCN Compendium™ Updated

NCCN has published the following updates to the Chronic Myelogenous Leukemia (CML) chapter of the NCCN Drugs & Biologics Compendium (NCCN Compendium™) to reflect updates to the preliminary 2011 version of the corresponding NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines™):

This update includes dasatinib and nilotinib as alternatives to imatinib for the primary treatment of newly diagnosed, Philadelphia chromosome or BCR-ABL positive CML (category 1 designation). In addition, dasatinib and nilotinib have been included as follow-up therapy in patients who have had inadequate responses to first-line therapy with a different multikinase inhibitor (category 2A designation). These updates are based on FDA approval (for nilotinib) and on a preliminary teleconference with the NCCN Guidelines Panel for CML.

For the complete updated versions of the NCCN Guidelines™ and the NCCN Compendium™ please visit NCCN.org.

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NCCN Guidelines™ and NCCN Compendium™ Updated