National Comprehensive Cancer Network

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NCCN Guidelines and Compendium Updated

Flash Update Sent July 17, 2012
NCCN has published updates to the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Breast Cancer Screening and Diagnosis. These NCCN Guidelines® are currently available as Version 1.2012.

  • The panel defined the starting age for screening recommendations for the following group of individuals:
    • For women who have a lifetime risk >20% as defined by models that are largely dependent on family history (eg, Claus, BRCAPRO, BOADICEA, Tyrer-Cuzick risk models), the panel recommends annual mammogram and clinical breast exam every 6-12 months, beginning at age 30 years, as well as consideration of annual breast MRI beginning at 30 years.
    • For women younger than 25 years who have received prior thoracic irradiation, the panel recommends encouraging  annual clinical breast exam starting 8-10 years after the radiation therapy.
  • For individuals with pedigree suggestive of or with known genetic predisposition, the panel added screening recommendations for Hereditary Breast and Ovarian Cancer (HBOC) and added a new footnote stating, "There is variation in recommendations for initiation of screening for different genetic syndromes. See NCCN Guidelines® for Genetic/Familial High Risk Assessment."
  • The Discussion section has been updated to reflect the changes in the algorithm.


For the complete updated version of these and all NCCN Guidelines, visit NCCN.org.