UPDATES: NCCN Guidelines® and NCCN Compendium®
NCCN Flash Update sent September 17, 2013
NCCN has published updates to the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) and the NCCN Drugs & Biologics Compendium (NCCN Compendium®) for Rectal Cancer. These NCCN Guidelines® are currently available as Version 1.2014.
- Workup (REC-2)
- Footnote "g" is new to the page: PET-CT does not supplant a contrast-enhanced diagnostic CT scan. PET-CT should only be used to evaluate an equivocal finding on a contrast-enhanced CT scan or in patients with strong contraindications to IV contrast.
- Resectable synchronous metastases (REC-5)
- Primary treatment option of staged or synchronous resection of metastases + rectal lesion removed.
- Surveillance (REC-7)
- Consider proctoscopy recommendation modified to every 6 mo x 3-5 y for patients status post LAR or transanal excision.
- Continuum of Care – Chemotherapy for Advanced or Metastatic Disease
- Bevacizumab added as an option in combination with FOLFOXIRI in initial therapy for advanced or metastatic disease. The category designation remains 2B. (REC-E 3 of 9)
- Footnote 3, last sentence modified: There are insufficient no data to support the routine use of Ca/Mg infusion to prevent oxaliplatin related neurotoxicity and therefore should not be done. (REC-E 5 of 9)
- Footnote 16 added: Regorafenib is a treatment option for patients who have progressed through all available regimens (e.g. KRAS mutant or KRAS WT with previous exposure to anti-EGFR inhibitor). (REC-E 5 of 9)
For the complete updated versions of the NCCN Guidelines, NCCN Compendium®, and the NCCN Chemotherapy Order Templates (NCCN Templates®), please visit NCCN.org.
To access the NCCN Biomarkers Compendium™, please visit NCCN.org/biomarkers.
To view the NCCN Guidelines for Patients®, please visit NCCN.org/patients.
Free NCCN Guidelines apps for iPad and Android tablets are now available! Visit NCCN.org/apps