Learning that a child has cancer is probably the most frightening news a parent can ever receive. Every day, City of Hope's team of researchers aggressively studies the science behind childhood cancers. These studies mean that our scientific team and their partners bring new therapies to kids as fast and safely as possible.
An essential element in the care of all pediatric patients at City of Hope is the unique ability to integrate advanced research and treatment within a humanitarian environment that provides emotional and spiritual support to patients and their families. Whenever possible, treatment programs are developed that minimize hospitalization and maximize the time spent at home and in other normal childhood activities. The pediatric oncologists have expertise in the management of all childhood cancers and are world-renowned experts in the areas listed below.
City of Hope's Pediatric Cancers Program specializes in treatment for many childhood cancers and conditions, including:
|General Information||800.826.HOPE (4673)|
|Referring Physician Line||800.826.HOPE (4673)|
|Location||Duarte, California (Los Angeles)|
Our pediatric patient rooms feature a comfortable sleeper chair for overnight visitors, video game systems and Internet access.The Pediatric Family Center at City of Hope Helford Clinical Research Hospital provides special accommodations for children and teen patients, including a playroom, teen room, family lounge and a library.
|Travel Assistance||Assistance with patient travel to City of Hope is available through our social work office. Contact 626.256.HOPE (4673), ext. 62282 for more information. Transportation may be available on a case-by-case basis.|
In keeping with our mission to care for the whole person – physically and emotionally – City of Hope is one of the few cancer centers in the country to offer patients and their caregivers temporary, on-site housing in a comfortable, home-like setting.
Each of the onsite 40 studio-style units in the Hope and Parson's Village offers the following amenities:
Transplant patients staying in the Hope & Parson's Village also have access to all of the facilities available on campus, such as the Sheri & Les Biller Patient and Family Resource Center, Supportive Care Resource Desk, Positive Image CenterSM, cafeteria, automated teller machine and Pastoral Care Services.
For more information contact the Hope & Parson's Village at 626.256.HOPE (4673), ext. 62380.Furthermore, close by and comfortable, many hotels and motels in neighboring communities offer special discounts to City of Hope patients and their families. Visit the "Patient and Visitor Guide" section of our Web site for a complete list.
|Social Support||Professionals in psychology, social work, recreational therapy, music and art therapy, and school relations provide individual attention and group activities for patients and their families. They provide individual attention and therapy as well as group activities for families, siblings, teens and children.|
|Home Health Care||Home health is coordinated with home health nursing agencies, pharmacy agencies, and hospice services.|
|Ages Treated||The Pediatric Cancers Program's treatment focus extends from infancy to older adolescents and young adults, ensuring a continuum of care through the years for this special group of patients. We also emphasize successful survivorship – continued surveillance to monitor and proactively address long-term effects of childhood cancer.|
|Barron Hilton Chair in Pediatrics Director, Pediatric Hematology/Oncology Professor, Pediatrics||Joseph Rosenthal, M.D.|
|Operate Multidisciplinary Teams||At City of Hope, our team of pediatric experts provides comprehensive care, offering both outstanding medical treatment and psychosocial support to young cancer patients and their family members. Pediatric oncologists, surgeons, radiation oncologists, pathologists, and other specialists work in concert to develop a targeted, effective treatment plan.|
|Cooperative Group Membership||Children's Oncology Group (COG)|
|Activities in Cooperative Group||Participation in COG disease committees including: Developmental Therapeutics, Ewing's Sarcoma, Osteosarcoma, Soft Tissue Sarcoma-Rhabdomyosarcoma, and Epidemiology and Late Effects. Physicians are principal investigators on numerous clinical trials.|
|Average Number of Pediatric Clinical Trials||25|
The Pediatric Neuro-oncology program at City of Hope is evaluating the potential of augmenting the antitumor response of T cells, a class of white blood cells that are part of the body's immune defenses against infection or cancerous cells. Through a process called adoptive T cell therapy, T cells that can recognize and attack cancer cells are isolated from patients, their numbers significantly increased outside of the body and then reinfused back into the patients, delivering highly specific and potentially minimally toxic therapy.
City of Hope's Pediatric Hematopoietic Cell Transplantation (HCT) Program provides lifesaving treatment to patients from infancy to early adulthood. Numerous blood diseases, including leukemia, lymphoma, Fanconi anemia and acquired aplastic anemia are treated. Also, HCT after high dose chemotherapy is performed for solid tumors such as neuroblastoma and sarcoma. In addition, unique clinical research protocols are offered, ensuring innovative therapy is available to appropriate patients.
Our comprehensive Musculoskeletal Tumor Program focuses on the diagnosis and treatment of pediatric cancers of the bone, muscle and cartilage. The multidisciplinary program is directing novel clinical studies investigating new therapies for children with these and other types of cancer, integrating precise surgical and reconstructive techniques thus optimizing their ability to be cured of their cancer while allowing them to continue to walk on their own limbs.
Our pediatric oncologists focus on developing innovative strategies for the treatment of high risk, poor prognostic solid tumors, including brain tumors. Investigating pediatric neuro-oncologic disease in the laboratory and then applying these strategies to clinical patient care is a special focus of research at City of Hope. These include:
The Pediatric Hemophilia and Sickle Cell Program provides care to children and young adults with inherited coagulation disorders such as hemophilia, and blood cell disorders such as sickle cell anemia. Current research focused on the accurate diagnosis and treatment of these diseases. Researchers are investigating risk factors leading to bleeding factor inhibitor development and immune tolerance induction regimens.
Immunotherapy, which stimulates or boosts the body's immune system so it can fight cancer more effectively, offers hope as a therapy for cancers that are incurable or difficult to treat such as relapsing leukemia, neuroblastoma and brain tumors. In addition to killing cancer cells, immunotherapy stimulates the patient's immune system to "watch out" for other cancer cells – known as immunosurveillance – and thus become part of the patient's continuing defense against cancer.
While almost 80 percent of all children with cancer are being cured of their diseases, the late effects of their treatment must be examined. City of Hope researchers have developed and continue to test their widely used quality-of-life survey in one of the largest cohorts of patients in the United States. Analysis of their results is critical to the development of future protocols. Extensive research, supported by the National Cancer Institute, the Leukemia and Lymphoma Society and the Lance Armstrong Foundation, is focusing on the health and well-being of the cancer survivor. Several studies are exploring the physical, psychological and neurocognitive health of our children treated for cancer. Furthermore, studies are under way to understand the contribution of genetic susceptibility and the environment in the development of late complications after successful treatment of childhood cancer.
Percent of children treated in each age range
Pediatric Oncology Program
|No. of Inpatient Beds||18|
|No. of Admissions||432|
|Average Length of Stay (days)||9.84|
|No. of New Outpatients||804 (total OP)|
|Total Outpatient Visits||5,062|
|No. of Bone Marrow Transplants||47|
|No. of Oncologists||8|