The
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Special Expertise |
· Blood and Marrow Transplantation · Brain Tumors · Bone Tumors · Leukemias · Lymphomas · Soft Tissue Sarcoma · Neuroblastoma · Pediatric Solid Tumors · Long-term Follow-up of Childhood and Adolescent Cancer · Psychology/Neuropsychology for Children and Adolescents In collaboration with the OSU Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute (OSUCCC-James) unique capabilities exist in: · Intra-operative radiotherapy (IORT) · High-dose-rate brachytherapy · Gamma knife · Intensity modulated radiation therapy (IMRT) |
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Pediatric Referral and Information |
General Hematology Oncology Blood and Marrow Transplantation Weekends, Holidays, and Weekdays after 5PM Phone: 614.722.2000 |
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General Information |
Nationwide Children's Hospital Operator |
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Referring Physician |
General Hematology Oncology |
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Location |
Pediatric Oncology services at the |
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Physical Plant |
The new Hematology/Oncology Unit at Nationwide Children's Hospital opened in 2002. The 31-bed, HEPA-filtered unit has eight rooms dedicated for Blood and Marrow Transplant patients. The unit contains a four-bed apheresis facility, a The outpatient clinic is in the |
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Travel Assistance |
Nationwide Children's Hospital social workers coordinate transportation for patients as needed. |
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Lodging |
A new Ronald McDonald House opened in place of the former one in 2005 on the hospital campus. There are four dedicated suites for immune-compromised patients and their families. The Clinical Services and Care Coordination department assists with lodging and can be reached at 614.722.6300. |
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Social Support |
Psychology, Nutrition, Dental, Child Life, Physical Therapy, Occupational Therapy, and Recreational Therapy specialists work as members of the interdisciplinary team to support the psychosocial, developmental, and emotional needs of patients and their families. An educational specialist is available as a liaison to the child's school. Tutoring and a school re-entry program are available. There is a sibling support group and a "Clubhouse" for siblings of children in the hospital. Nationwide Children's Hospital runs an annual weekend camp for children with hematologic and cancer diagnoses. Visitation for parents is 24 hours a day. |
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Home Health Care/Hospice |
Nationwide Children's Hospital offers many services to meet the needs of children at home throughout central Children's also offers hospice services for pediatric oncology patients. This service is JCAHO-accredited and certified by Medicare/Medicaid. It is the only pediatric hospice program in central |
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Ages Treated |
Children of all ages, from birth to age 20, are treated at Nationwide Children's Hospital, including young adults with pediatric disease diagnoses. |
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Pediatric Oncology Director |
Thomas G. Gross, MD, PhD Phone: 614.722.3552 |
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Director, Pediatric Blood and Marrow Transplant Program |
Amanda M. Termuhlen, MD |
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Multidisciplinary Teams |
All children and adolescents diagnosed with cancer are treated by a multidisciplinary team consisting of a pediatric oncologist, nurse practitioner, nurses, psychologists, social workers, child life specialists, education specialists, pharmacists, and therapists. There are formal teams that care for patients with brain or bone tumors, long-term survivors, and those undergoing blood or marrow transplantation. |
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Cooperative Group Membership |
· Children's Oncology Group (COG) · Childhood Cancer Survivor Study (CCS) · Pediatric Blood and Marrow Transplant Consortium · International Bone Marrow Transplant Registry (research member) · National Bone Marrow Donor Program |
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Cooperative Group Activities |
The Pediatric Blood and Cancer Program at Children's Hospital is one of the largest and most active members of the Children's Oncology Group. The Division Chief, Tom Gross, MD, PhD, is the chair of the Non-Hodgkin's Lymphoma Strategy Group and chairs a protocol for the treatment of post-transplant lymphoproliferative disease. The associate chief, Amanda Termuhlen, MD, is chair of a Rare and Cutaneous Non-Hodgkin Lymphoma Registry, vice-chair of the treatment protocol for all newly diagnosed lymphoblastic lymphomas, and a member of the protocol committee running a trial for relapsed B-cell lymphomas. She is on the Voting Body, Adolescent and Young Adult Committee, and is a member of both the Hematology/Oncology and the Stem Cell Transplant discipline. Fred Ruymann, MD, former principal investigator in the Children's Cancer Oncology Group and active in the Intergroup Rhabdomyosarcoma committees, chairs the Children's Oncology Group Membership Committee. Several advanced practice nurses and clinical research associates serve on Children's Oncology Group committees, including late effects and the treatment of neuroblastoma, nasopharyngeal carcinomas, and Hodgkin's disease. Clinical research is supported by a staff of Clinical Research Associates and managed by Barb Pugh, RN, MS, CCRP. The clinical research office can be contacted at 614.722.3568. |
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Average Number of Trials |
100 |
In 2004, the Center for Childhood Cancer was established as a new
An important component of the Center for Childhood Cancer is the
Scientists in the Center for Childhood Cancer are listed below:
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Research Scientist |
Expertise |
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Tom Gross, MD, PhD |
Transplant and Tumor Immunology |
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Long-Sheng Chang, PhD |
Retinoblastoma, Neurofibromatosis |
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Mary Beth Ross, MD, PhD |
Leukemia; Genome profiling |
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Dawn Chandler, PhD |
Pre-mRNA splicing; Rhabdomyosarcoma |
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Julie Gastier-Foster, PhD |
Molecular genetic testing |
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Jayah Lin, PhD |
Jak/Stat signaling and cancer |
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Christopher Pierson, MD, PhD |
Brain Tumors and Neuromuscular Diseases |
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Corey Raffel, MD, PhD |
Neurosurgery |
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BioPathology |
Blood and Marrow Transplantation
The Nationwide Children's Hospital Pediatric Blood and Marrow Transplantation (BMT) Program works in collaboration with the adult BMT Program at the OSUCCC-James Cancer Hospital and Solove Research Institute. Bone marrow processing, HLA typing, and cytogenetics are shared between the two institutions. The Pediatric Blood and Marrow Transplant program is accredited by the Federation for Accreditation of Cellular Therapies (FACT), is an independent
· Autologous (one's own bone marrow or peripheral blood stem cell)
· Allogeneic (a donor's marrow-related or unrelated)
· Umbilical cord blood
The Pediatric Blood and Marrow Transplant Program patients are cared for at Nationwide Children's Hospital with a full complement of multidisciplinary team members and pediatric sub-specialists. Nationwide Children's Hospital has a Pediatric Intensive Care Unit with four designated HEPA-filtered Bone Marrow Transplant beds that offer 24-hour in-house pediatric intensivist coverage. The BMT physician team is sub-specialized into those caring for patients with leukemia, solid tumors, non-malignant disorders, and genetic/metabolic or immune deficiency disorders. There are dedicated multidisciplinary clinics for chronic graft-vs.-host disease patients and long-term survivors of BMT. The BMT program works closely with two immunologists, and the program conducts clinical research in oncology as well as brain tumors, non-cancer conditions, and graft-vs.-host disease. The program is supported by four full-time nurse practitioners who provide outpatient clinic coverage and 24-hour house coverage of BMT patients Monday through Friday. There are two BMT coordinators to facilitate referral and pre-transplant evaluations of patients. For a BMT referral, call 614.722.3558.
Brain Tumors
Randal
Bone Tumors
Nick Yeager, MD, oncologist, and Joel Mayerson, MD, orthopedic oncologist, along with a dedicated bone tumor pediatric nurse practitioner, staff a comprehensive bone tumor clinic. They jointly meet with new patients and collaborate on medical and surgical management. Mayerson is a national expert on limb-salvage procedures using cutting-edge surgical techniques and innovative pediatric prosthetics.
Behavioral Research
The Nationwide Children's Hospital Blood and Cancer Program works very closely with two research psychologists who are studying pediatric cancer patients. Ongoing research includes:
· A study of communication between parent and child about cancer diagnosis and prognosis
· Grief in the family that has lost a child to pediatric cancer
· Obesity/bone problems in children finishing chemotherapy for leukemia
· The late neuropsychological effects of brain tumor therapy
· The efficacy of massage and humor therapy during bone marrow transplantation
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