National Comprehensive Cancer Network

Members Only
NCCN Oncology Research Program (ORP)
NCCN Mirvetuximab Soravtansine Research Grant Opportunity - Submit by February 15, 2016
NCCN Afatinib Combination Research Grant Opportunity - Submit by February 19, 2016
Study Proposal Submission-NCCN RMS
ORP Recent News
ORP Affiliate Research Consortium
ORP Scientific Publications
ORP for Industry
ORP Investigator Steering Committee
ORP Testimonials
Clinical Trials at NCCN Member Institutions
Find NCCN ORP Funded Clinical Trials at NCCN Member Institutions
ORP Grant History
Informed Consent Language Database
Points to Consider on the Best Practices for Biorepositories, Registries and Databases
NCCN Shared Resources (Members Only
ORP Disclosure Policy
Call for Abstracts: NCCN General Poster Session
NCCN Collaboration with the National Business Group on Health
NCCN Health Information Technology Licensees

NCCN Research & Business Resources

Vanderbilt-Ingram Cancer Center
Nashville, Tennessee

Adult Oncology Services


More than 150 clinicians from a number of cancer-related fields work collaboratively to care for cancer patients and their families, with an emphasis on providing the very best treatment for each patient, with compassion and in a specialized, multidisciplinary way. Collaboration is a hallmark of our cancer center, in our clinical care delivery as well as our research.

Patients, family members and referring clinicians may learn more about our services, our clinical trials and second opinion consultations through our Cancer Information Program (CIP), staffed by four full-time, experienced oncology nurses. This service, established in 1997, handles more than 3,000 new inquiries (phone calls, e-mails, letters) annually and approximately 700-800 follow-up communications each month. The Information Program reachable at 800.811.8480.

Multidisciplinary Teams

Weekly tumor conferences are held for most major tumor sites:

o Thoracic

o Breast

o Genitourinary

o Gastrointestinal

o Neuro-oncology

o Gynecologic oncology

o Bone and tissue

o Head and neck

o Leukemia and lymphoma

o Melanoma

These teams include all disciplines involved in the care of these patients, including oncologists, hematologists, surgeons and surgical oncologists, radiation oncologists, radiologists, pathologists, nurses, social workers, psychologists, and other specialists.

In the past year, more formal multidisciplinary clinics have been developed for newly diagnosed breast cancer patients and women at high risk for breast cancer. More info at

Special Expertise

· Bone marrow/stem cell transplantation

· Laparoscopic colorectal cancer surgery


· Robotic surgery for prostate cancer

· Experimental therapeutics including Phase I clinical trials

· High-dose brachytherapy for prostate and breast cancer

· Clinical proteomics

· Imaging including PET, functional MRI, spectroscopy, fluorescence imaging in brain and other tumors

· Head and neck cancers

· Orthopedic cancers and sarcomas

· Genitourinary cancers (prostate and renal in particular)

· Lung cancers

· Melanomas

· Breast cancer

· Inherited cancer risk

· Cancer survivorship and wellness after treatment

· Breast MRI

General Information

General Information


Referring Physician Line

800.811.8480 (M-F 8:00 AM - 4:30 PM Central time)

800.288.5000 (evenings, weekends)


Nashville, Tennessee


Henry-Joyce Cancer Clinic and Chemotherapy Infusion Center (now undergoing expansion now to double size/capacity to 116,000 square feet and 46 infusion stations), Outpatient Stem Cell Transplant Unit, a 27-bed inpatient Myelosuppression Unit, the Center for Radiation Oncology, various surgical clinics, , all located within Vanderbilt Hospital and Clinic on the main Vanderbilt Medical Center campus; the Vanderbilt Breast Center, which will move in early 2009 to an innovative new community-based health and wellness center, Vanderbilt Health One Hundred Oaks; freestanding radiation therapy centers in Montgomery and Williamson counties; a satellite oncology clinic in Williamson County; and clinical trials affiliates through a dozen partner oncology practices and hospitals in five states.

Travel Assistance

Vanderbilt-Ingram has an American Cancer Society Transportation Grant and also works with ACS and other providers of transportation. Contact: 615.322.7459 or


Several non-profit organizations offer housing options, some requiring referral by our social worker. These include the American Cancer Society's Hope Lodge; Hospital Hospitality House; and nearby apartments with arrangements to provide housing for bone marrow transplant patients and caregivers. Contact: 615.343.7776 or

Stem Cell Transplant Program

The Blood and Bone Marrow Transplant (BMT) Program at Vanderbilt-Ingram Cancer Center offers the full spectrum of transplant types (autologous, related and unrelated allogeneic, reduced-intensity and umbilical cord transplant). These transplants may be conducted in an inpatient setting or in our Outpatient Transplant Unit (OTU) depending on the needs of the individual patient.

The program offers BMT for patients with myeloma, non-Hodgkin's lymphoma, acute leukemias, Hodgkin's disease, chronic leukemias, myelodysplastic syndrome, severe aplastic anemia, germ cell tumors and myeloproliferative disorders. Services include a 27-bed inpatient, HEPA-filtered transplant unit on the 11th floor of Vanderbilt University Hospital, a 13-room outpatient transplant unit staffed 365 days a year, and a long-term follow-up clinic. More information, including outcomes data, available at Contact: 615.936.1803.

Brain Tumor Center

Vanderbilt-Ingram's Brain Tumor Center brings together clinicians from neurosurgery, neuro-oncology, radiation oncology, pediatric neuro-oncology, radiosurgery, neuroradiology, neuro intensive care and neuropathology. We specialize in treatment of benign and malignant tumors of the brain (both primary and metastatic) and have special expertise in treating tumors of the skull base and the pituitary region. Our surgical team, which perform approximately 400 major brain tumor surgeries each year, offers sophisticated expertise including use of functional MRI pre-operative scanning, intraoperative mapping techniques and "awake craniotomy."

Our Brain Tumor Board meets weekly to review cases of patients with brain tumors and to discuss treatment options. Patients or physicians wishing to have their cases reviewed by the Brain Tumor Board may call 615.343.4152.Results are provided to referring physicians or patients within one week of review.

Thoracic Oncology Program

Vanderbilt-Ingram Cancer Center offers one of the most active and recognized programs in the nation for lung cancer. This highly organized program focuses on efficient and coordinated multi-specialty care, multi-modality and laboratory research, and education of our own trainees on a national and international basis.

A weekly Clinical Thoracic Oncology Conference allows each subspecialty group to give input on a particular patient followed by a treatment plan that is formulated by the appropriate specialists.

Same-day testing is available for CT scans, bone scans, MRI scans, pulmonary function testing, immediate pathological interpretations of outside biopsies and bronchoscopy. The Thoracic Oncology faculty work closely together in the multimodality management of patients. Referring physicians are notified of management decisions and recommendations usually within 24 hours of the patient's visit to the clinic. Contact: 615.322.6053

Center for Radiation Oncology

Vanderbilt-Ingram's Center for Radiation Oncology offers treatment in three locations: at the main medical center campus in Nashville and at free-standing radiation oncology centers in Franklin, Tenn. (Vanderbilt-Ingram Cancer Center at Franklin) and Clarksville, Tenn. (Gateway-Vanderbilt Cancer Treatment Center). Our services include: three-dimensional conformal radiation therapy (3D-CRT); intensity modulated radiation therapy (IMRT); stereotactic radiotherapy; image-guided radiation therapy (IGRT); brachytherapy; systemic radiation therapy; radioimmunotherapy, and investigational radiation therapies. In early 2009, the Center will being offering robotic stereotactic radiosurgery. More information at

REACH for Survivorship: Resources, Education, Advocacy, Clinical Care, Health Promotion

A comprehensive survivorship program is being developed at Vanderbilt to focus on the long-term physical, emotional and practical issues facing cancer survivors and family members. This clinic, to be initially located within the Henry-Joyce Cancer Clinic, will provide services for all cancer survivors, regardless of type of cancer, age at diagnosis, and where they received their cancer treatment. Survivors receive a comprehensive evaluation, so they can understand the long-term physical and emotional problems that they may face following cancer treatment. This includes review of pertinent oncology medical records, a risk-adapted history and physical examination, screening tests for adverse long-term outcomes related to the cancer and its therapy, referral to sub specialists and rehabilitation services, and provision of detailed educational information. This educational information includes a Survivorship Care Plan which details the patient's oncology treatment, potential long-term effects of treatment and recommendations for monitoring. REACH for Survivorship also will provide access to research to improve cancer survival and quality of that survivorship; patient and health care provider education; patient advocacy; and access to wellness and fitness programs.

Cancer Prevention and Screening

Through the Office of Patient and Community Education and the Office of Minority Affairs, dozens of community programs are offered throughout the year to promote cancer prevention and early detection.

Vanderbilt Corporate Relations includes cancer information in its health fairs and other programming for key employers in our region; Vanderbilt participates in an annual free community skin cancer screening event, provides free skin cancer screenings for Vanderbilt faculty and staff each spring and offers free head and neck cancer screenings in conjunction with the local VA Medical Center and the Yul Brynner Foundation. Contact: 615.936.5855.

Support Services & Supportive Care

Office of Patient Support and Integrative Care

This service is designed to address the spectrum of physical, psychosocial, emotional, and other needs of patients that exist in conjunction with and in addition to their medical and disease management needs. Services include a specialized Pain and Symptom management clinic, nutrition services by two registered dietitians, psychological services and social work consultation and assistance. Contact: 615.322.7463 or

Vanderbilt Center for Integrative Health

Cancer is one of the leading diagnoses for patients referred to this center, which combines traditional medicine with complementary and alternative approaches that are scientifically proven safe and effective. The center offers comprehensive integrative health and/or psychologic consultations with MD- and PhD-trained professionals. More information at 615.343.1554 or

Patient and Family Support Services

Staffed by a full-time manager and a cadre of dedicated volunteers, this service attends to the comfort of patients and families during their clinic visits. Refreshments, visits by specially trained pets, entertainment by local songwriters and musicians, a wig service and other services are offered. Contact: 615.343.7776

Patient and Family Resource Center

This center, staffed by a full-time manager and conveniently located next to the main clinic waiting area, offers a variety of resources for patient and family education and information. Contact: 615.322.9799.

Home Care Services

Vanderbilt Home Care Services includes two agencies: a Medicare-certified agency and a non Medicare-certified agency. Staffing includes nurses; physical, occupational, and speech therapists and assistants; home health aides/PCAs; medical social workers; office support for both agencies. The care is provided by a multidisciplinary team coordinated under the direction and supervision of the patient's physician.


Vanderbilt-Ingram Cancer Center works closely with Alive Hospice, a Nashville based, nonprofit hospice covering Nashville and 11 surrounding counties. Alive Hospice also offers a 30-bed inpatient full-service residence for patients who cannot be cared for at home - or who need a transition from hospital to home. Alive Hospice provides a full time registered nurse (RN) to work with the staff and patients/families at Vanderbilt who are ready to transition to hospice care. This RN admits the patients to hospice services assuring a smooth and seamless change.

Rehabilitation Services

Rehab services are provided in a variety of ways. The bone marrow/stem cell transplant program has a full-time physical therapist to work with both the in- and outpatients throughout the course of treatment. Other inpatients receive services from the Vanderbilt physical therapists based on physician request for service. There is a large outpatient program where patients may receive services after discharge from the hospital. Patients needing inpatient rehab services may be transferred to the 80-bed Vanderbilt Stallworth Rehabilitation Hospital. The hospital provides both in- and outpatient services for a variety of diseases/complications requiring rehabilitation. With additional space to be made available when the current clinic expansion is completed, we anticipate offering physical therapy and rehab services in the cancer clinic for our oncology outpatients as well.

Case management/social work

Vanderbilt has a unique way of providing case management, social work and utilization management. The three providers work together in a triad, focusing on a set patient population. They work closely with the direct care providers to assure that services needed are arranged for prior to discharge, that hospital days are approved, and to help plan for the psychosocial needs of the patient/family during the hospital stay and after discharge. The Cancer Patient Care Center has 3 Master's prepared case managers, 4 Master's prepared social workers, 1 utilization manager and a Bachelor's prepared social worker. The case managers work largely with the inpatients while the social workers cover both in and outpatients.

Clinical and Research Efforts

Vanderbilt-Ingram Cancer Center's mission is to conduct high-impact research, with an emphasis on translational work to bridge laboratory discoveries with clinical advances. In addition to offering a full-range of innovative clinical trials, Vanderbilt-Ingram has a number of special, collaborative and patient-oriented research initiatives including:

· Phase I and Phase II clinical trial agreements with NCI

· Southern Community Cohort Study

· Three Specialized Programs of Research Excellence (SPORE) grants in lung, gastrointestinal and breast cancers

· Digestive Disease Center grant

· U54 Minority Partnership Grant (including clinical trials initiative) with Meharry Medical College

· Clinical Proteomic Technology Assessment Grant

· Mouse Models of Human Cancer Grant

· Many others (see


Adult Oncology Program (2006 data)

No. of Inpatient Beds (Medical and Surgical)

No. of Admissions

Average Length of Stay (days)

No. of New Outpatients

No. of Oncologists (Medical and Surgical)

858 total licensed beds (Vanderbilt Hospital)

27 dedicated cancer beds (myelosupp unit)

28 gyn beds (gyn onc uses)

89 general med

69 general surg

1,876 discharges classified by DRG; 4,918 discharges classified by ICD-9 code

5.5 for ICD-9 classified discharges; 6.7 for DRG classified discharges

4,915 new patient visits (oncology, hematology, BMT and surgical oncology)

Surg oncologists: 11

Med oncologists:40

Plus ~ 20 fellows

Cooperative Group Membership

Cooperative Group Membership List







Activities in Cooperative Group

Clinical trial participation and leadership

Average Number of Adult Clinical Trials

160 (therapeutic and correlative)