The NCCN Clinical Practice Guidelines in Oncology™ for Myelodysplastic Syndromes (MDS) have been updated and published by the National Comprehensive Cancer Network. The current version is 1.2010.
In the updated version, the category of evidence and consensus for recommending azacytidine for the treatment of higher risk MDS patients (IPSS risk category INTERMEDIATE-2 and High) is now Category 1. Previously, this recommendation was Category 2A. Updates also include the addition of azacytidine, decitabine, or participation in a clinical trial as recommended options for higher risk patients who relapse following allogeneic hemopoietic stem cell transplant.