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NCCN Guidelines for Kidney Cancer Updated to Include Pazopanib for Advanced Disease

The NCCN Clinical Practice Guidelines in Oncology™ for Kidney Cancer have been updated to incorporate the recently approved therapy pazopanib as a treatment option for patients with advanced renal cell carcinoma.

The NCCN Guidelines Panel for Kidney Cancer has added pazopanib as a first-line therapy option for those with predominant clear cell histology (category 1 designation) and for those with non clear cell histology (category 3 designation). In addition, pazopanib has been incorporated into the options for subsequent therapy for those with predominant clear cell histology following cytokine therapy (category 1 designation) and following other tyrosine kinase inhibitors (category 3 designation).