Cancer Centers in the News

The following links highlight some of the most up-to-date news from the 26 NCCN Member Institutions. The media coverage below includes major national news outlets, industry magazines, medical journals, and press releases.

The news is listed in reverse chronological order for ease of use.

July 31, 2015
Exercise during Adolescence Linked to Lowered Risk of Death Later

Women who participated in exercise as adolescents had a reduced risk of death from cancer and all causes in their middle and older ages, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

This study’s lead author, Sarah J. Nechuta, MPH, PhD, is assistant professor of medicine at Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center in Nashville, Tennessee—one of the 26 NCCN Member Institutions. 

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July 31, 2015
Molecule in Donor Cells May Be Key to Better Outcomes for Transplant Patients

For patients with leukemia, lymphoma, and other blood cancers, a blood or marrow transplant (BMT) can be a potential cure. But when the transplant uses marrow or blood stem cells from a donor, it can have two effects — one harmful and the other helpful.

Now, with a five-year, $2.01 million grant from the National Cancer Institute, Xuefang Cao, MD, PhD, Department of Immunology, is leading research aimed at shutting down the bad side effect and increasing the good one. Both are caused by the donor’s “killer T cells” — white blood cells that are part of the immune system.

Roswell Park Cancer Institute is one of the 26 NCCN Member Institutions.

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July 30, 2015
Simple Mouth Rinse Could Help Predict Recurrence of HPV-Related Oropharyngeal Cancers

Oropharyngeal cancer patients who were found to have detectable traces of human papillomavirus type 16 (HPV16) in their saliva following cancer treatment are at an increased risk for recurrence, a study led by researchers at the Johns Hopkins Bloomberg School of Public Health has found.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins is one of the 26 NCCN Member Institutions. 

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July 29, 2015
Scientists at City of Hope and UCLA Stop Tumor Growth with Nanoparticles

Scientists at City of Hope and UCLA have become the first to inhibit the expression of a protein, called TWIST that promotes tumor invasion and metastasis when activated by cancer cells. As such, they’ve taken the first step in developing a potential new therapy for some of the deadliest cancers, including ovarian cancer and melanoma.

City of Hope Comprehensive Cancer Center is one of the 26 NCCN Member Institutions. 

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July 29, 2015
Targeted Therapy Shows Effectiveness against a Subtype of the Brain Tumor Medulloblastoma

A targeted therapy already used to treat advanced skin cancer is also effective against the most common subtype of the brain tumor medulloblastoma in adults and should be considered for treatment of newly diagnosed patients, according to research led by St. Jude Children’s Research Hospital.

St. Jude Children’s Research Hospital/University of Tennessee Health Science Center is one of the 26 NCCN Member Institutions. 

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July 28, 2015
'Jaw-Dropping': Medicare Deaths, Hospitalizations AND Costs Reduced

Mortality rates among Medicare patients fell 16% from 1999 to 2013. That’s equal to more than 300,000 fewer deaths a year in 2013 than in 1999, said cardiologist Harlan Krumholz, lead author of a new study in the Journal of the American Medical Association (JAMA) and a professor at the Yale School of Medicine.

Yale Cancer Institute/Smilow Cancer Hospital is one of the 26 NCCN Member Institutions.  

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July 27, 2015
New Drug for Blood Cancers Now in Five Phase II Clinical Trials

Researchers at University of California, San Diego School of Medicine have established the safety and dosing of a new drug for treating blood cancers. The findings are published online July 27 in The Lancet Haematology.

The drug is a small molecule inhibitor that suppresses the activity of a signaling pathway believed to contribute to a variety of blood cancers’ eventual resistance to standard chemotherapy treatments.

UC San Diego Moores Cancer Center is one of the 26 NCCN Member Institutions.

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July 27, 2015
Gene Therapy May Improve Survival of Patients with Recurrent Ovarian Cancer

Use of gene therapy to deliver a protein that suppresses the development of female reproductive organs may improve the survival of patients with ovarian cancer that has recurred after chemotherapy, which happens 70 percent of the time and is invariably fatal.  In their report, a Massachusetts General Hospital research team describes how a single injection of a modified version of Mullerian Inhibiting Substance, a protein critical to sexual development, carried on a commonly used viral vector suppressed the growth of chemotherapy-resistant ovarian tumors in a mouse model.

Dana-Farber/Brigham and Women’s Cancer Center | Massachusetts General Hospital Cancer Center is one of the 26 NCCN Member Institutions.

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July 27, 2015
Fertility after Cancer: Young Woman Less Likely to be Told about Options

A new nationwide study by researchers at Fred Hutchinson Cancer Research Center and Seattle Children’s reveals that young male patients were twice as likely as young women to be counseled on ways to preserve their fertility, such as freezing sperm or eggs.

Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance is one of the 26 NCCN Member Institutions. 

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July 27, 2015
Yale Study Identifies ‘Major Player’ in Skin Cancer Genes

A multidisciplinary team at Yale, led by Yale Cancer Center members, has defined a subgroup of genetic mutations that are present in a significant number of melanoma skin cancer cases. Their findings shed light on an important mutation in this deadly disease, and may lead to more targeted anti-cancer therapies.

Yale Cancer Center/Smilow Cancer Hospital is one of the 26 NCCN Member Institutions. 

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July 27, 2015
Will One Bad Sunburn Give You Skin Cancer?

This year, about 250,000 people will be diagnosed with melanoma and 60,000 people will die from this most dangerous form of skin cancer. While the increased risk accompanying one bad burn is still imprecise, studies show that the overall lifetime risk of developing melanoma climbs 80 percent with five blistering burns in childhood.

University of Colorado Cancer Center is one of the 26 NCCN Member Institutions.      

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July 23, 2015
Doctors Speak Out Against 'Unsustainable' Rise In Cancer Drug Prices

According to 118 leading oncologists, there's some good news about cancer drugs. New ones are being developed faster than ever. Here's the bad news. A lot of cancer patients can't afford them. In a commentary published Thursday by the journal of the Mayo Clinic Clinic Cancer Center, the oncologists call the steady rise in the price of cancer drugs unsustainable.

Mayo Clinic Cancer Center is one of the 26 NCCN Member Institutions. 

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July 23, 2015
Researchers Decode Molecular Action of Combination Therapy for a Deadly Thyroid Cancer

In their bid to find the best combination of therapies to treat anaplastic thyroid cancer (ATC), researchers on Mayo Clinic Cancer Center’s Florida campus demonstrated that all histone deacetylase (HDAC) inhibitors are not created equal.

In testing multiple HDAC inhibitors in combination with the chemotherapy drug paclitaxel, known to give some benefit for this aggressive cancer, they found that class II HDAC inhibitors signal through a newly discovered pathway to promote synergy with chemotherapy treatment.

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July 23, 2015
Study Explores Protein’s Role in Inflammation-Associated Cancer

A protein that transports the micronutrient selenium and has antioxidant functions may protect against colitis-associated carcinoma — colon cancer that develops in patients with inflammatory bowel disease, according to a new Vanderbilt-Ingram Cancer Center-led study.

The findings, reported in the July 2015 issue of the Journal of Clinical Investigation, could suggest strategies for reducing colon cancer risk in these patients.

Vanderbilt-Ingram Cancer Center is one of the 26 NCCN Member Institutions. 

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July 23, 2015
For Prostate Cancer Patients, Risk-Specific Therapies Now More the Norm

After decades of overtreatment for low-risk prostate cancer and inadequate management of its more aggressive forms, patients are now more likely to receive medical care matched to level of risk, according to a study by researchers at UCSF Helen Diller Family Comprehensive Cancer Center—one of the 26 NCCN Member Institutions. 

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July 23, 2015
Lymph Node Radiation May Halt Breast Cancer Recurrences

Two new studies show promising results for the use of radiation therapy to prevent breast cancer from coming back.

The research shows that when patients with breast cancer received radiation therapy to their lymph nodes – not just the area of the breast where cancer occurred – cancer did not recur in the original site or spread to other parts of the body. Interestingly, the results were the same regardless of whether the cancer had spread to the lymph nodes.

Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute is one of the 26 NCCN Member Institutions. 

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July 22, 2015
Lymph Node Radiation May Halt Breast Cancer Recurrences

Two new studies show promising results for the use of radiation therapy to prevent breast cancer from coming back.

The research shows that when patients with breast cancer received radiation therapy to their lymph nodes – not just the area of the breast where cancer occurred – cancer did not recur in the original site or spread to other parts of the body. Interestingly, the results were the same regardless of whether the cancer had spread to the lymph nodes.

Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute is one of the 26 NCCN Member Institutions. 

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July 22, 2015
Poor Survival in Multiple Myeloma Patients Linked to Genetic Variation

As part of a multi-institutional effort, researchers with Huntsman Cancer Institute at the University of Utah have found that multiple myeloma patients with a genetic variation in the gene FOPNL die on average one to three years sooner than patients without it. The finding was identified with a genetic mapping technique, genome wide association studies (GWAS), and verified in patient populations from North America and Europe. This was the first study to survey the entire human genome for genetic variation influencing survival, and included a total of 1,635 patients.

Huntsman Cancer Institute at the University of Utah is one of the 26 NCCN Member Institutions.

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July 22, 2015
Moffitt Cancer Center Researchers Develop First Genetic Test to Predict Tumor Sensitivity to Radiation Therapy

Recent advances in the understanding of cancer have led to more personalized therapies, such as drugs that target particular proteins and tests that analyze gene expression patterns in tumors to predict a patient’s response to therapy. Moffitt Cancer Center researchers have contributed to these advances by developing the first test that analyzes the sensitivity of tumors to radiation therapy. They discovered that colon cancer metastases have varying sensitivity to radiation therapy based on their anatomic location.

Moffitt Cancer Center is one of the 26 NCCN Member Institutions. 

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July 1, 2015
Finding Better Ways to Fight Cancer Means Starting with the Basics (Dana-Farber/Brigham and Women’s Cancer Center | Massachusetts General Hospital Cancer Center)

Having a team of scientists working on basic science at a cancer institute may seem unusual, but Kai W. Wucherpfennig, MD, PhD, co-chair of the Department of Cancer Immunology and Virology at Dana-Farber Cancer Institute, says it makes perfect sense.

Dana-Farber/Brigham and Women’s Cancer Center | Massachusetts General Hospital Cancer Center is one of the 26 NCCN Member Institutions.

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July 1, 2015
Salmonella Bacterium Could Prove Potent Foe to Aggressive Form of Pancreatic Cancer (City of Hope Comprehensive Cancer Center)

Patients with an aggressive form of pancreatic cancer known as pancreatic ductal adenocarcinoma currently have few good therapeutic options, with most medications able to increase survival by only a few months while exacting a high physical toll. City of Hope researchers appear to have found a better option, one that uses the Salmonella bacterium.
City of Hope Comprehensive Cancer Center is one of the 26 NCCN Member Institutions.

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June 30, 2015
Intercontinental Oncology Partnership Brings Access to Specialized Cancer Care to Nigeria (Roswell Park Cancer Institute)

America’s oldest cancer center and one of the world’s newest oncology centers are partnering to improve access to cancer prevention, screening and care for the people of Nigeria. Roswell Park Cancer Institute (RPCI) and Lakeshore Cancer Center (LCC) have announced an affiliation that will see Roswell Park faculty providing clinical consultations to assist LCC oncologists, who will also have access to both training at RPCI and continuing professional education seminars they can participate in remotely.

Roswell Park Cancer Institute is one of the 26 NCCN Member Institutions.

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June 30, 2015
Protein’s Impact on Colorectal Cancer is Dappled (UC San Diego Moores Cancer Center)

Researchers at University of California, San Diego School of Medicine have discovered a cell signaling pathway that appears to exert some control over initiation and progression of colorectal cancer, the third leading cause of cancer-related death in the United States. A key protein in the pathway also appears to be predictive of cancer survival rates.
UC San Diego Moores Cancer Center is one of the 26 NCCN Member Institutions.

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June 30, 2015
10 Years to Cancer Cures 'Actually Plausible,' Fred Hutch President Says (Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance)

The future of cancer therapy looks “incredibly promising,” Dr. D. Gary Gilliland, president and director of Fred Hutchinson Cancer Research Center, said Tuesday.
 
“It’s actually plausible that in 10 years we’ll have curative therapies for most if not all human cancers,” Gilliland told hundreds of industry and research leaders from around the world who were gathered in Seattle at the 2015 Life Science Innovation Northwest conference, an event hosted by the Washington Biotechnology & Biomedical Association.

Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance is one of the 26 NCCN Member Institutions. 

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June 30, 2015
Mayo Clinic Study Suggests which Glioblastoma Patients May Benefit from Drug Treatment (Mayo Clinic Cancer Center)

Clinicians testing the drug dasatinib, approved for several blood cancers, had hoped it would slow the aggressive growth of the deadly brain cancer glioblastoma; however, clinical trials to date have not found any benefit. Researchers at Mayo Clinic, who conducted one of those clinical trials, believe they know why dasatinib failed — and what to do about it.

Mayo Clinic Cancer Center is one of the 26 NCCN Member Institutions.

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June 30, 2015
Similarities between Embryos and Breast Tumors Identified (The University of Texas MD Anderson Cancer Center)

It may seem incredulous, but breast tumors may have something in common with embryos … at least in mice, say researchers at The University of Texas MD Anderson Cancer Center—one of the 26 NCCN Member Institutions. 

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