NCCN Guidelines for Patients® | Esophageal Cancer - page 42

NCCN Guidelines for Patients
: Esophageal Cancer
Version 1.2013
Part 5: Squamous cell carcinomas
This chart lists the treatment options for when surgery
can’t be done. For a Tis tumor, endoscopic treatment—
EMR or ablation—is a safe option. EMR followed by
ablation can remove T1a and T1b tumors. Instead of
endoscopic treatment, chemoradiation may be given for
a T1b tumor that may have spread beyond the reach of
endoscopic treatment. The recommended chemotherapy
regimens for chemoradiation are:
Preferred regimens
• Cisplatin and fluoropyrimidine (5-FU or capecitabine)
• Oxaliplatin and fluoropyrimidine (5-FU or
• Paclitaxel and carboplatin
Other regimens
• Paclitaxel and cisplatin
• Docetaxel and cisplatin
• Irinotecan and cisplatin
• Paclitaxel and fluoropyrimidine (5-FU or
• Docetaxel and fluoropyrimidine (5-FU or
Next steps:
When you are finished with cancer
treatment, read Part 5.3 for follow-up testing.
Nonsurgical options
TNM scores
Primary treatment
Tis, N0, M0
T1a, N0, M0
EMR, or
T1b, N0, M0
EMR then ablation
EMR then ablation, or
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