NCCN Guidelines for Patients® | Esophageal Cancer - page 46

NCCN Guidelines for Patients
: Esophageal Cancer
Version 1.2013
Part 5: Squamous cell carcinomas
This chart maps the treatment options for people healthy
enough for surgery and who have esophageal cancers
within the neck. Sometimes esophageal cancers in the
neck can’t be first treated with surgery or you may not
want surgery. In these cases, concurrent chemoradiation
to cure the cancer is recommended. The recommended
chemotherapy regimens for chemoradiation are:
Preferred regimens
• Cisplatin and fluoropyrimidine (5-FU or capecitabine)
• Oxaliplatin and fluoropyrimidine (5-FU or
• Paclitaxel and carboplatin
Other regimens
• Paclitaxel and cisplatin
• Docetaxel and cisplatin
• Irinotecan and cisplatin
• Paclitaxel and fluoropyrimidine (5-FU or
• Docetaxel and fluoropyrimidine (5-FU or
TNM scores
Primary treatment
Treatment results
No signs of cancer
T1 – T4a disease
T4b or M1 disease
Adjuvant treatment
Supportive care
Esophagectomy, or
Supportive care
Tumors within the neck
Start follow-up testing
T2, N0, M0
T3, N0, M0
T4a, N0, M0
T1b, N+, M0
T2, N+, M0
T3, N+, M0
T4a, N+, M0
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