NCCN Guidelines for Patients® | Esophageal Cancer - page 49

49
NCCN Guidelines for Patients
®
: Esophageal Cancer
Version 1.2013
Part 5: Squamous cell carcinomas
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This chart lists the treatment options for when surgery can’t be done. If you are
able to undergo chemoradiation, it is recommended to try to cure the cancer.
The recommended chemotherapy regimens for chemoradiation are:
Preferred regimens
• Cisplatin and fluoropyrimidine (5-FU or capecitabine)
• Oxaliplatin and fluoropyrimidine (5-FU or capecitabine)
• Paclitaxel and carboplatin
Other regimens
• Paclitaxel and cisplatin
• Docetaxel and cisplatin
• Irinotecan and cisplatin
• Paclitaxel and fluoropyrimidine (5-FU or capecitabine)
• Docetaxel and fluoropyrimidine (5-FU or capecitabine)
Definitions:
!
Read pages 16–17
for definitions of
TNM scores.
TNM scores
Primary treatment
Nonsurgical options
Chemoradiation,
Chemotherapy,
Radiation therapy, or
Supportive care
T2, N0, M0
T3, N0, M0
T4a, N0, M0
T1b, N+, M0
T2, N+, M0
T3, N+, M0
T4a, N+, M0
T4b, N+, M0
Concurrent
chemoradiation:
Chemotherapy and
radiation therapy given at
the same time
Supportive care:
Treatment for symptoms
that are caused by cancer
or by cancer treatment
Trachea:
The airway
between the throat and
bronchi; also called the
windpipe
Acronyms:
5-FU
=
fluorouracil
CT
=
computed tomography
GI
=
gastrointestinal
PET
= positron emission
tomography
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