NCCN Guidelines for Patients® | Esophageal Cancer - page 54

54
NCCN Guidelines for Patients
®
: Esophageal Cancer
Version 1.2013
Part 5: Squamous cell carcinomas
Your ability to do activities is called performance status.
Your doctor can rate your performance status by one of
two scales:
ECOG (
E
astern
C
ooperative
O
ncology
G
roup)
Performance Scale
• A
score of 0
means you are fully active.
• A
score of 1
means you are able to do all self-care
activities but are unable to do hard physical work.
• A
score of 2
means you are able to do all self-care
activities and spend most of waking time out of bed
but you are unable to do any work.
• A s
core of 3
means you are unable to do all self-
care activities and any work and spend most of
waking time in bed.
• A
score of 4
means you are fully disabled.
KPS (
K
arnofsky
P
erformance
S
tatus)
• A
score of 0 to 49
means you are unable to care
for yourself.
• A
score of 50 to 79
means you are unable to work
and some assistance is needed.
• A
score of 80 to 100
means you are able to do your
normal work and activities.
You may be able to have chemotherapy if you have a
ECOG score of 2 or less or a KPS score of 60 more. Two
back-to-back chemotherapy regimens are recommended.
Three regimens may be given if you are healthy enough
and have good performance status. If you do have
chemotherapy, it is important for your doctors to assess
for side effects on a regular basis.
First-line chemotherapy regimens are listed next. If you
are given a 5-FU regimen, leucovorin may be added
to limit side effects of the chemotherapy. If the cancer
doesn’t respond to first-line regimens, your doctor may
give you a second-line regimen. Alternative regimens
may be used with first- or second-line regimens.
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