NCCN Guidelines for Patients
Melanoma, Version 1.2014
Removal of a sample of tissue from the skin to test for
A careful review of the skin to check for abnormal-looking
spots that may be signs of skin cancer.
An organ to the left of the stomach that helps protect the
body against disease.
The process of rating and describing the extent of cancer in
stereotactic radiosurgery (SRS)
A type of radiation therapy that delivers a high dose of
radiation to a small, specific area.
Below the skin.
sun protection factor (SPF)
A rating of the level of protection sunscreen products provide
against the UV rays from the sun.
At, on, or near the top or surface.
superficial spreading melanoma
The most common type of melanoma; it grows slowly and
spreads from a mole.
Treatment given to relieve the symptoms caused by cancer
or side effects caused by cancer treatment. Also called
An operation to remove or repair a part of the body.
The normal-looking tissue around the edge of a tumor
removed during surgery.
Drugs used to treat cancer cells throughout the body.
Drugs that specifically target and kill cancer cells.
A written course of action through cancer treatment and
true local scar recurrence
Cancer not completely removed or destroyed by treatment,
with cancer cells found in or right next to the surgical
scar where the first melanoma was removed. Also called
An overgrowth of cells.
A decrease in the size of the tumor.
The tumor’s top skin layer is broken or missing.
Whether or not the tumor’s top skin layer is present and
intact (not ulcerated) or is broken or missing (ulcerated).
Long-lasting inflammation that causes tears (ulcers) in the
lining of the colon (organ that changes eaten food from liquid
A test that uses sound waves to take pictures of the inside of
ultraviolet (UV) energy
Invisible light energy that comes from the sun and tanning
beds. UV energy has a wavelength shorter than visible light
but longer than x-rays.
ultraviolet-A (UVA) energy
Long-wave invisible light energy that comes from the sun
and tanning beds.
ultraviolet-B (UVB) energy
Short-wave invisible light energy that comes from the sun
and in small amounts from tanning beds.
Changing the rating of the extent of cancer in the body—the
cancer stage—from a lower, less extensive stage to a higher,
more extensive stage.
A treatment used to help the immune system (the body’s
natural defense against disease) prevent a disease.
A drug that treats melanoma by targeting a certain abnormal
change in the instructions in cells for making and controlling