NCCN Guidelines for Patients
Part 1: About melanoma
One half or side of the mole does not match the other half or side.
The edges of the mole are ragged or notched.
The color of the mole is not the same throughout. There may be different shades of tan, brown, or black and
sometimes patches of red, blue, or white.
The mole is wider than ¼ inch—the top of a pencil eraser. However, doctors have found melanomas as
small as ⅛ inch.
The mole has changed in size, shape, color, or texture over the past few weeks or months.
Figure 6. ABCDE rule: Moles with and
without signs of cancer
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