NCCN Guidelines for Patients® | Melanoma - page 20

20
NCCN Guidelines for Patients
®
: Melanoma
Version 1.2013
Part 2: Overview of cancer tests
Pathology results
Breslow thickness.
The depth of tumor growth measured in millimeters.
Ulceration status.
Whether or not the tumor’s top skin layer is present and intact (not ulcerated) or is broken
or missing (ulcerated).
Dermal mitotic rate.
A measure of how many tumor cells are actually growing and dividing.
Clark level.
A scale of tumor depth with 5 scores based on which layer of skin the tumor has grown into (invaded).
Peripheral margin status.
Presence or absence of cancer cells in the normal-looking tissue around the
sides of a tumor.
Deep margin status.
Presence or absence of cancer cells in the normal-looking tissue under a tumor.
Microsatellitosis.
Tiny tumors near the main tumor seen with a microscope.
Tumor location.
The area of the body that contains the tumor.
Tumor regression.
A decrease in the size of the tumor.
Tumor-infiltrating lymphocytes.
Presence or absence of white blood cells.
Vertical growth phase.
Direction of tumor growth is down into the skin.
Angiolymphatic invasion.
Melanoma has grown into (invaded) lymph or blood vessels.
Neurotropism.
Melanoma cells are able to grow into (invade) nerves.
Histologic subtype.
Grouping of cancer types based on cancer cell qualities.
Pure desmoplasia.
Presence or absence of dense connective tissue.
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