NCCN Guidelines for Patients® | Melanoma - page 83

NCCN Guidelines for Patients
®
Melanoma, Version 1.2014
81
5.5
Treatment guide
Metastatic melanoma
Chart 6. Systemic therapy for advanced or metastatic melanoma
Drug name
Type of drug
Preferred regimens
Ipilimumab
Immunotherapy
Vemurafenib
Targeted therapy
Dabrafenib
Targeted therapy
Dabrafenib + trametinib
Targeted therapy
Clinical trial
--
High-dose interleukin-2
Immunotherapy
Other regimens
Trametinib
Targeted therapy
Imatinib (for
c-kit
mutated tumors)
Targeted therapy
Dacarbazine
Chemotherapy
Temozolomide
Chemotherapy
Nab-paclitaxel
Chemotherapy
Paclitaxel
Chemotherapy
Paclitaxel and carboplatin
Chemotherapy
Dacarbazine- or temozolomide-based combination
chemotherapy/biochemotherapy (including cisplatin and
vinblastine + interleukin-2 or interferon alfa)
Chemotherapy/
Biochemotherapy
1...,73,74,75,76,77,78,79,80,81,82 84,85,86,87,88,89,90,91,92,93,...108
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