NCCN Guidelines for Patients® | Melanoma - page 94

94
NCCN Guidelines for Patients
®
: Melanoma
Version 1.2013
Part 9: Dictionary
Melanocytes
Cells that give skin its color and are
located in the lower part of the top
layer of the skin (epidermis).
Melanoma
A cancer that starts in melanocytes—
cells that give skin its color and are
located in the top layer of the skin
(epidermis).
Melanoma in situ
Cancer cells are only in the outer
layer of the skin (epidermis).
Metastases
Tumors formed by cancer cells that
have spread from the first tumor to
other parts of the body.
Metastasis
The spread of cancer cells from the
first tumor to another body part.
Metastasize
The act of cancer cells spreading from
the first tumor to another body part.
Metastatic
Containing cancer cells that have
spread from the first tumor.
Metastatic lymph node
A lymph node (group of special
disease-fighting cells) containing
cancer cells that spread from the first
tumor.
Metastatic recurrence
Cancer that has come back after
treatment in a part of the body far
away from the first tumor.
Microsatellitosis
Tiny tumors near the main tumor that
can only be seen with a microscope (a
tool that uses lenses to see things the
eyes can’t).
Microscope
A tool that uses lenses to see things
the eyes can’t.
Microscopic
Something so small it can’t be seen
by the naked eye.
Mole
A spot on the skin formed by a cluster
of cells that make melanin (substance
that gives skin its color).
Monoclonal antibody
A type of immune system protein
made in a lab that can attach to
substances in the body such as
cancer cells.
Negative margins
There are no cancer cells in the
normal-looking tissue around the
tumor removed during surgery.
Neoadjuvant treatment
Treatment given before the main or
primary treatment.
Neurotropism
Melanoma cells are able to invade
nerves.
Nodal basin
A cluster of lymph nodes (groups of
special disease-fighting cells) located
close to one another in a certain area
of the body such as near a tumor.
Nodal extracapsular extension
The tumor in the lymph node has
grown beyond the edge of the node.
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