NCCN Guidelines for Patients® | Melanoma - page 98

NCCN Guidelines for Patients
®
Melanoma, Version 1.2014
96
Glossary
Dictionary
mole
A spot on the skin formed by a cluster of cells that make
melanin (substance that gives skin its color).
monoclonal antibody
A type of immune system protein made in a lab that can
attach to substances in the body such as cancer cells.
negative margins
There are no cancer cells in the normal-looking tissue
around the edge of the tumor removed during surgery.
neoadjuvant treatment
Treatment given before the main or primary treatment.
neurotropism
Melanoma cells are able to grow into (invade) nerves.
nodal basin
A group or cluster of lymph nodes (groups of special
disease-fighting cells) located close to one another in a
certain area of the body such as near a tumor.
node-negative
Cancer cells are not found in lymph nodes (groups of special
disease-fighting cells located throughout the body).
node-positive
Cancer cells are found in lymph nodes (groups of special
disease-fighting cells located throughout the body).
nodular melanoma
A type of melanoma that has a dome shape and may grow
more quickly into the second layer of skin (dermis) than other
melanomas.
non-melanoma skin cancer
Cancer of the skin that starts in cells other than melanocytes
(cells that give skin its color).
nonmetastatic recurrence
Cancer that has come back after treatment but has not
spread to parts of the body far away from the first tumor.
observation
A period of scheduled follow-up testing to watch for signs of
cancer spread (metastasis) or return (recurrence).
palliative treatment
Treatment given to relieve symptoms caused by cancer
or side effects caused by cancer treatment. Also called
supportive care.
pathologic stage
A rating of the extent of melanoma in the body based on
tests of lymph nodes and other tissue removed during
surgical treatment.
pathologist
A doctor who’s an expert in testing cells and tissue to find
disease.
pathology report
A document with information about cancer cells and tissue
that were removed from the body and examined with a
microscope for disease.
peginterferon alfa-2b
A long-acting type of interferon—a drug used to activate the
body’s natural defense against disease.
pelvis
The body area between the hipbones.
peripheral margin status
Presence or absence of cancer cells in the normal-looking
tissue around the sides of a tumor removed during surgery.
persistent melanoma
Cancer not completely removed or destroyed by treatment;
persistent melanoma is found in or right next to the surgical
scar where the first melanoma was removed. Also called true
local scar recurrence.
physical exam
A review of the body by a health expert for signs of disease.
positive margins
There are cancer cells in the normal-looking tissue around
the edge of the tumor removed during surgery.
positron emission tomography (PET) scan
A test that uses radioactive material to see the shape and
function of organs and tissues inside the body.
primary treatment
The main treatment used to rid the body of cancer.
primary tumor
The first mass of cancer cells in the body.
prognosis
The likely or expected course and outcome of a disease.
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