NCCN Guidelines for Patients® | Malignant Pleural Mesothelioma - page 13

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NCCN Guidelines for Patients
®
: Malignant Pleural Mesothelioma
Version 1.2012
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Part 3: Testing for mesothelioma
Pleural biopsy
A pleural biopsy removes one or more samples of the pleura. The samples
are then sent to a lab to be tested for cancer cells and biomarkers of cancer,
such as cytokeratin. There are a few ways that a pleural biopsy can be done.
Options are a CT-guided core biopsy, an Abrams needle biopsy, an open
biopsy, or a thoracoscopic biopsy. Thoracoscopic biopsy is the preferred
method.
A CT-guided core biopsy uses pictures from a CT scan to guide a needle into
your body. First, your skin will be cleaned and numbed with local anesthesia.
Next, the needle will be inserted through a small cut and guided into your chest
between your ribs. Then, the sample will be removed by the sharp end of the
needle and stored in a hollow space within the needle.
Figure 4. Thoracentesis
Illustration Copyright © 2012 Nucleus
Medical Media, All rights reserved.
Definitions
Allergic reaction:
Symptoms caused when
the body is trying to rid
itself of invaders
Biomarker:
A substance
found in body fluid or
tissues that may be a sign
of cancer
Cytokeratin:
Type of
protein found on cells that
line the inside and outside
surfaces of the body
Local anesthesia:
A
controlled loss of feeling
in a small area of the body
from drugs
Pleura:
The tissue lining
around the lungs
Pleural cavity:
The space
between the two pleura
layers
Radiologist:
A doctor
who’s an expert in reading
imaging tests
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