NCCN Guidelines for Patients
Malignant Pleural Mesothelioma, Version 1.2014
Am I at risk?
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Some patients with mesothelioma have had no clear
exposure to asbestos. This suggests that there may
be other causes of the disease. A gene mutation is
an abnormal change in the instructions for making
and controlling cells. Recent studies show that having
a mutation in the
gene may increase the risk
for mesothelioma. However, the cause and effect
relationship between asbestos exposure and the
mutation is uncertain. This gene mutation can
rarely be passed down from parents to children. Prior
radiation therapy, such as that given for Hodgkin’s
lymphoma, may also be a cause.
American Cancer Society
National Cancer Institute
Mesothelioma Applied Research Foundation
Asbestos Disease Awareness Organization
• Asbestos is a group of minerals made of tiny
fibers that are strong and flexible.
• Asbestos can break into tiny pieces that may
be breathed in or swallowed.
• Asbestos is the only known cause of
mesothelioma, though some patients with
mesothelioma have had no clear exposure.