NCCN Guidelines for Patients® | Malignant Pleural Mesothelioma - page 26

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NCCN Guidelines for Patients
®
: Malignant Pleural Mesothelioma
Version 1.2012
Part 5: Treating mesothelioma
Definitions
Conformal radiation
therapy:
Radiation beams
are shaped to match the
shape of the cancer using
imaging scans
EBRT:
Radiation therapy
received from a machine
outside the body
First-line treatment:
The
first set of treatments given
to treat a disease
Second-line treatment:
The next treatment(s) given
when first-line treatment
fails
Side effect:
An unplanned
physical or emotional
response to treatment
CT
= Computed
tomography
EBRT
= External beam
radiation therapy
Acronyms
Stage I – III epithelioid or mixed mesothelioma
The main types of EBRT used for mesothelioma include:
• 3D-CRT (three-
d
imensional
c
onformal
r
adiation
t
herapy) – Radiation
is given in small doses for a few weeks with x-ray beams that match
the shape of the tumor,
• IMRT (
i
ntensity-
m
odulated
r
adiation
t
herapy) – Radiation is given in small
doses for a few weeks with x-ray beams of different strengths based on the
thickness of the tumor,
• Tomotherapy – A type of IMRT, a tomotherapy machine takes CT scans and
delivers radiation, and
• Proton beam therapy – Radiation is given using proton beams, which deliver
more radiation at the end rather than throughout the beam.
Conformal radiation therapy is the preferred method by NCCN doctors. IMRT,
tomotherapy, and proton beam therapy are newer radiation therapy methods.
They should only be used in experienced cancer centers or according to a specific,
detailed treatment plan called a protocol.
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