NCCN Guidelines for Patients® | Multiple Myeloma - page 15

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NCCN Guidelines for Patients™: Multiple Myeloma
Version 1.2012
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Definitions:
Besides blood, doctors also test urine to look for signs of disease. Urine tests can
be used to diagnose myeloma, assess if organs are working well, and check the
results of cancer treatments. Urine is often tested for:
Tumor burden
• UPEP (
u
rine
p
rotein
e
lectro
p
horesis) measures the amount of M-protein
in urine. Urine is collected for 24 hours then sent to a lab for testing.
• UIFE (
u
rine
i
mmuno
f
ixation
e
lectrophoresis) identifies the type of the
M-protein. Only light chains, not heavy chains, are found in urine.
• Total protein is a test that measures the amount and type of protein in urine
over a 24-hour period.
2.3 Urine tests
Blood plasma:
The
yellowish part of blood that
carries blood cells
Bone marrow:
The soft
tissue in the center of bones
BUN:
Waste from the liver
filtered out of blood by the
kidneys
Calcium:
A mineral in bones
Creatinine:
Waste from
muscles filtered out of blood
by the kidneys
Electrolyte:
Minerals in
blood that carry an electric
charge
Free light chain:
Fragment
of an M-protein
Immune system:
The group
of organs and cells that
defends the body against
illnesses
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