NCCN Guidelines for Patients® | Multiple Myeloma - page 17

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NCCN Guidelines for Patients™: Multiple Myeloma
Version 1.2012
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Definitions:
2.4 Tissue tests
• Multiparameter flow cytometry is an additional test to measure the amount of
myeloma cells in the bone marrow. This test is used by doctors to judge the
risk of progression to active myeloma in patients without symptoms. A high
number of myeloma cells is a sign that the myeloma will likely progress.
• Bone marrow immunohistochemistry measures the number of myeloma cells.
• Plasma cell labeling index is a test that shows what percentage of the
myeloma cells are dividing and how fast they are doing it. Cells that are
dividing quickly are a sign of cancer that will spread fast.
Figure 6. Bone marrow biopsy
Illustration Copyright © 2012 Nucleus Medical Media, All rights reserved.
Active myeloma:
Myeloma
that is causing symptoms
Genes:
The instructions
inside cells for making new
cells and controlling how
cells behave
Imaging test:
A test that
makes pictures of the
insides of the body
Microscope:
A tool that
uses lenses to see things
the eyes can’t
Pathologist:
A doctor
who’s an expert in testing
cells to find disease
Progression:
The growth
of cancer
Solitary plasmacytoma:
One mass of myeloma cells
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