NCCN Guidelines for Patients® | Multiple Myeloma - page 28

26
NCCN Guidelines for Patients
®
Multiple Myeloma, Version 1.2014
3
Treatments for myeloma
Systemic therapy
Chemotherapy
Chemotherapy drugs kill fast-growing cells throughout
the body, including cancer cells and normal cells.
Many people refer to this treatment as “chemo.”
Cancer cells grow fast, so chemotherapy works
well to stop new cancer cells from being made.
Chemotherapy can also affect normal cells. Some
chemotherapy drugs can also cause much damage to
your bone marrow.
Chemotherapy is given in cycles of treatment days
followed by days of rest. The cycles vary in length
depending on which drugs are used. Often, the cycles
are 14, 21, or 28 days long. Chemotherapy cycles
also give the body a chance to recover before the
next treatment. Most of the chemotherapy drugs listed
in
Chart 3.1
are liquids that are slowly injected into
a vein. Some are a pill that is swallowed. The drugs
travel in the bloodstream to treat cancer throughout
the body.
Steroids
Steroids are a type of drug used to relieve swelling
and inflammation, but some steroids have anti-cancer
effects. For myeloma, steroids can be used alone to
treat myeloma or used with chemotherapy, targeted
therapy, or both.
See Chart 3.1
for a list of steroids
used to treat myeloma.
Chart 3.1 Drug treatments for multiple myeloma
Generic name
Brand name (sold as)
Type of drug
Bendamustine
Treanda
Chemotherapy
Bortezomib
Velcade
Targeted therapy
Carfilzomib
Kyprolis
Targeted therapy
Cisplatin
Platinol
Chemotherapy
Cyclophosphamide
Cytoxan
Chemotherapy
Dexamethasone
Decadron
Steroid
Doxorubicin
Adriamycin
Chemotherapy
Etoposide
VePesid
Chemotherapy
Interferon
Immunomodulator
Lenalidomide
Revlimid
Immunomodulator
Liposomal doxorubicin
Doxil
Chemotherapy
Melphalan
Alkeran
Chemotherapy
Pomalidomide
Pomalyst
Immunomodulator
Prednisone
Steroid
Thalidomide
Thalomid
Immunomodulator
Vincristine
Oncovin
Chemotherapy
Vorinostat
Zolinza
Targeted therapy
1...,18,19,20,21,22,23,24,25,26,27 29,30,31,32,33,34,35,36,37,38,...82
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