NCCN Guidelines for Patients® | Multiple Myeloma - page 46

NCCN Guidelines for Patients™: Multiple Myeloma
Version 1.2012
Smoldering myeloma
Primary treatment
• Blood tests:
▪▪ CBC
▪▪ BUN, creatinine, calcium
▪▪ Serum quantitative immunoglobulins, SPEP, and SIFE
▪▪ Serum free light chain assay as needed
• Urine tests:
▪▪ Total protein
• Imaging tests:
▪▪ Bone survey every year or for symptoms
▪▪ MRI as needed
▪▪ PET/CT scan as needed
• Tissue tests:
▪▪ Bone marrow aspiration and biopsy as needed
▪▪ Multiparameter flow cytometry as needed
Observation with testing every 3 – 6 months
Clinical trial, or
Part 5.3 describes the care of smoldering myeloma.
This myeloma often takes months to years to
progress to active myeloma. For this reason,
treatment isn’t needed right away. Instead, a clinical
trial or observation is recommended. Observation
means that your doctor will watch for cancer growth
with regular follow-up tests. Many of the tests used
for diagnosis and to assess symptoms are repeated
to check the status of the cancer. Follow-up tests are
suggested every 3 to 6 months.
Next steps:
If the cancer grows, go back to the
page 41 to find out which pages to read next.
5.3 Smoldering multiple myeloma
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