NCCN Guidelines for Patients® | Ovarian Cancer - page 49

Part 5: Treatment with cancer drugs
NCCN Guidelines for Patients
: Ovarian cancer
Version 1.2013
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Post-chemotherapy treatment
If you have stage II, III, or IV ovarian cancer, you may receive additional
treatment after completing primary chemotherapy. The treatment options
depend on how the cancer responded to primary chemotherapy. A complete
response is when all signs and symptoms of the cancer have completely
disappeared after treatment—no signs of cancer on imaging tests, physical
exam, or CA-125 blood tests. A partial response is when some but not all of
the signs and symptoms of the cancer have disappeared—a decrease in the
size of tumors and/or decrease in CA-125 levels. Persistent disease is cancer
that did not respond to chemotherapy at all. Progressive disease is cancer that
responded to chemotherapy initially and then began to grow or spread again
Additional treatment for stage II, III, IV
Test results
Complete response
all signs and symptoms of cancer
have completely disappeared
Clinical trial,
Start follow-up, or
Paclitaxel for 12 cycles
Partial response
some or most signs and symptoms
of cancer have disappeared
Clinical trial,
Start recurrence treatment, or
Start follow-up
Persistent or progressive disease
cancer didn’t respond to chemo, or
responded then began to grow again
Clinical trial,
Supportive/palliative care
Start recurrence treatment, or
A protein made by
ovarian cancer cells as well
as normal cells
Chemotherapy cycle:
Days of treatment followed
by days of rest
Primary chemotherapy:
The first or main
chemotherapy drug or
drugs given to treat cancer
Side effect:
An unplanned
physical or emotional
response to treatment
See Part 2 on
page 12 for more
test details and
CA-125 =
Cancer antigen
Complete blood
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