NCCN Guidelines for Patients
Stages I and II Breast Cancer, Version 1.2014
Doctors plan treatment based on test results, your
overall health, your wishes, and other factors. One
option for treatment is joining a clinical trial. Clinical
trials are the treatment option that is preferred by
NCCN experts. Some basic information about clinical
trials is given below.
New tests and treatments aren’t offered to the public
as soon as they’re made. They need to be studied. A
clinical trial is a type of research that studies a test or
treatment. Clinical trials study how safe and helpful
tests and treatments are. When found to be safe
and helpful, they may become tomorrow’s standard
of care. Because of clinical trials, the tests and
treatments in this booklet are now widely used to help
New tests and treatments
go through a series of
clinical trials to make sure
they’re safe and work.
Without clinical trials, there
is no way to know if a test or
treatment is safe or helpful.
Clinical trials have four phases:
Phase I trials
Aim to find the best dose of a new drug with the fewest
Phase II trials
Assess if a drug works for a specific type of cancer.
Phase III trials
Compare a new drug to the standard treatment.
Phase IV trials
Test new drugs approved by the FDA (
in many patients with different types of cancer.