NCCN Guidelines for Patients® | Stages I and II Breast Cancer - page 62

NCCN Guidelines for Patients
Stages I and II Breast Cancer, Version 1.2014
Hormone therapy
Should I take hormone therapy?
Should I take hormone therapy?
Deciding factors
You may receive hormone therapy if the breast
cancer cells are hormone receptor–positive. If you
are pregnant, you may receive hormone therapy
after your baby is born. Hormone therapy lowers
the chances (risk) of the cancer returning after local
treatment, chemotherapy, or both. How likely is it that
the cancer will return differs among women. Doctors
predict the return of cancer based on features of
the cancer. The recommendations of the NCCN
doctors are presented next. Their recommendations
are based on the type of breast cancer, size of the
tumors, and other factors.
Lower-risk breast cancers
Tubular and mucinous breast cancers have a low
risk of returning after local treatment. See page 35
for more information about these breast cancers. The
recommendations for hormone therapy for lower-risk
breast cancer are listed below.
Lower-risk breast cancer
| Hormone receptor-positive
Size of breast tumor
Size of lymph node tumor
Do I need hormone therapy?
Smaller than 1.0 cm None or tiny (≤2.0 mm) tumors No
1.0 to 2.9 cm
None or tiny (≤2.0 mm) tumors Consider hormone therapy
3.0 cm or larger
None or tiny (≤2.0 mm) tumors Yes
Any size
Larger than 2.0 mm
Hormone therapy for breast cancer isn’t recommended
when the breast tumor is smaller than 1.0 cm and
there is no or little cancer spread to the axillary lymph
nodes. Hormone therapy isn’t needed because
the results of local treatment are often very good.
However, you may want to take hormone therapy
to lower your risk for cancer in the other breast and
lower your small risk for recurrence in the treated
breast. The results of local treatment for breast tumors
between 1.0 and 2.9 cm in width are still very good,
but hormone therapy may be considered. Hormone
therapy should be taken when the breast tumor is
3.0 cm or larger or at least one tumor in your axillary
lymph node is 2.0 mm or larger.
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