National Comprehensive Cancer Network

NCCN Guidelines™ & Clinical Resources

NCCN Categories of Evidence and Consensus

• Category 1: The recommendation is based on high level evidence (e.g. randomized controlled trials) and there is uniform NCCN consensus.
• Category 2A: The recommendation is based on lower level evidence and there is uniform NCCN consensus.
• Category 2B: The recommendation is based on lower level evidence and there is nonuniform NCCN consensus (but no major disagreement).
• Category 3: The recommendation is based on any level of evidence but reflects major disagreement.

All recommendations are category 2A unless otherwise noted.

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