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Roswell Park Comprehensive Cancer Center
Buffalo, New York
877.275.7724 (877.ASK.RPCI)

Find a clinical trial >

Pediatric Oncology


The major goals of Roswell Park Comprehensive Cancer Center's Department of Pediatrics are to provide state-of-the-art treatment to children with malignant disorders, to conduct basic and clinical research aimed at improving cure rates and decreasing long-term toxicities, to identify and manage the acute and long-term complications of therapy, and to establish new and effective coping interventions for patients and their families. Over the years, Roswell Park has pioneered many treatment innovations and cancer-related discoveries.

The pediatric oncologists have expertise in the management of all childhood cancers and are world-renowned experts in the areas listed below.


Special Expertise

  • Brain Tumors
  • Long-Term Survivors
  • Lymphoma
  • Orthopedic Oncology
  • Stem Cell and Blood and Marrow Transplantation
  • Adolescent and Young Adult Oncology


General Information


General Information Line

877.275.7724 (877.ASK.RPCI) Monday through Friday, 9:00 AM to
5:30 PM, EST. A voice mail system is available after hours and calls are returned the next business day.

International Calls (outside USA and Canada)



Buffalo, New York

Facilities Description

The campus has undergone a major modernization. This includes a brand-new inpatient unit and ambulatory care clinic, staffed by specialized nurses trained in pediatric oncology. Air handling has been designed to minimize risks of infection for immunocompromised patients.

Travel Assistance

Social workers provide assistance to patients and families in securing transportation and lodging. Patients and their families from Roswell Park use DoubleTree Club Hotel adjacent to the Roswell Park Comprehensive Cancer Center campus. The DoubleTree may be accessed from the first floor of Roswell Park's Basic Science building via an enclosed walkway. For information and reservations, call 716.845.0112. Their Web site is www.doubletree.Hilton.com/en/dt/hotels/index.jhtml?moreDesc=true&ctyhocn=BUFNYDT

The Kevin Guest House, operated by volunteers, is the oldest hospitality house in the United States and the prototype for the 60 Ronald McDonald Houses across the country. The Kevin Guest House provides clean, safe, and peaceful living arrangements for families of patients receiving care at Roswell Park Comprehensive Cancer Center. This is part of the National Association of Hospital Hospitality Houses.

A Ronald McDonald House and a Hope Lodge are nearby.

Social Support

The Psychosocial Department offers support groups for pediatric patients and parents. All families are seen by a social worker and have on-going access to psychosocial support. A child-life specialist works with the children on the inpatient unit and the outpatient clinic.

Home Health Care

Several home care vendors are available to patients. The Essential Care Program provides psychosocial support to children with life-threatening illnesses in addition to their home care needs.

Ages Treated

Children from birth to age 21 are treated.


Clinical and Research Information


Chairman, Pediatric Oncology

Kara Kelly, MD

Multidisciplinary Teams

Each patient has a primary physician, nurse, and nurse practitioner that work with the patient throughout treatment and follow-up. A social worker, psychologist and child-life specialist are part of the team and work with patients and families as needed.

Cooperative Group Membership

Children's Oncology Group (COG)

Cooperative Group Activities

Participation in COG committees includes:

  • Hodgkin Lymphoma
  • Voting Body
  • Neuroscience
  • Central Nervous System
  • Pathology
  • Nominating
  • Late Effects
  • Adolescent Young Adult

Oncologists are Principal Investigators on numerous studies.

Average Number of Pediatric Clinical Trials


Pediatric Clinical Trial Coordinator

Charmaine Uebelhoer, CRC

Stephanie Guilford, CRC  


Research Efforts

Researchers at Roswell Park are studying the late effects of therapy for childhood cancer. Late organ toxicities and psychosocial adjustments in long-term survivors are being investigated. COG studies of the neuro-cognitive effects of treatment of acute lymphocytic leukemia states and of babies with brain tumors will be coordinated in Buffalo, as well as the biology study in pediatric Hodgkin lymphoma. Pediatric oncologists are involved in research to develop new targeted therapies including basic and translational research focused on targeted therapies in pediatric lymphoma. Clinical outcomes between teens and young adults with common AYA diseases are being studied.

Special Expertise

Brain Tumors

Treatment through the multidisciplinary brain tumor program includes investigational drug therapies, the use of stereotactic radiosurgery in selected cases, and long-term follow-up, including the management of late effects. Stereotactic radiation therapy enables a high dose of radiation to be delivered to a small, intracranial area without harming adjacent tissue.

Long-Term Survivors

Roswell Park Cancer Institute operates a Long-Term Follow-Up Clinic, created to provide specialized medical care and counseling to former childhood cancer patients. It was one of the first of its kind in the nation. Dramatic success in the treatment of childhood cancers has resulted in a population of survivors who may have unique problems, such as difficulty in finding employment, questions concerning their reproductive capability because of cancer and its treatment, and the possibility of developing other malignancies later in life. This Clinic assists cancer survivors in building full, productive lives.


Investigators at Roswell Park Comprehensive Cancer Center sit on the Hodgkin lymphoma core committee for the Children's Oncology Group (COG) and have chaired multiple institutional trials for Hodgkin lymphoma.

State-of-the-art diagnostic screening and cutting-edge therapies, including several immunotherapeutic trials (i.e., unlabeled and radiolabeled monoclonal antibody trials in the treatment of B-cell lymphomas), institutional and cooperative group (i.e., CALGB) trials, as well as standard and high-dose transplant therapies, are available.

Roswell Park investigators piloted clinical trials in advanced small non-cleaved-cell lymphoma, which contributed to subsequent Children's Oncology Group (COG) multi-institutional trials. Survival for patients with advanced stage disease has improved significantly, with more than 70 percent of patients cured.

Orthopedic Oncology

Roswell Park introduced a new surgical technique that saves the limbs of over 90 percent of soft tissue sarcoma patients whose options were once limited to amputation. The multidisciplinary team emphasizes limb-sparing procedures, new drug therapies, and rehabilitation.

Adolescent and Young Adult Oncology Program

The AYA program was developed in 2011 to recognize the unique needs of patients who are between 15 – 39 years of age. The team consists of a physician, social worker and psychologist and addresses an AYA’s concerns throughout their cancer experience. The program also helps with fertility preservation by discussing the risks of infertility associated with therapy and in assisting the patient’s pursuit of fertility preservation, such as sperm cryopreservation.

Stem Cell and Blood and Marrow Transplantation

The Roswell Park BMT team utilizes allogeneic and autologous blood and marrow transplantation, stem cell infusion, and umbilical cord transplantation in the treatment of pediatric malignancies and bone marrow failure states.


Percent of children treated in each age range

Age Range





Percent Treated







Pediatric Oncology Program

No. of Inpatient Beds

No. of Oncologists/Related Specialists

No. of Admissions

Average Length of Stay (days)

No. of New Outpatients

Total Outpatient Visits

No. of Bone Marrow Transplants