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The Fred & Pamela Buffett Cancer Center is a partnership between Nebraska Medicine and the University of Nebraska Medical Center (UNMC) in Omaha, Nebraska

Contact Nebraska Medicine today at 402.559.5600.

Find a clinical trial >


In 1995, Nebraska Medicine (formerly Nebraska Medical Center) joined the National Comprehensive Cancer Network (NCCN) as a founding member and remains active in the network today. In 2015, based on a generous lead donation—along with a public-private partnership—a new flagship cancer center was established as the Fred & Pamela Buffett Cancer Center, part of the Nebraska Medicine Cancer Network and the University of Nebraska Medical Center (UNMC)

The Buffett Cancer Center consists of a 10-story cancer research tower and 8-story inpatient hospital and outpatient center that includes medical, surgical and radiation oncology clinics, a 24/7 infusion center, radiology, lab services, radiation therapy and surgical services.

The Buffett Cancer Center coordinates basic and clinical cancer research, patient care, and educational programs, and facilitates the application of new knowledge about the etiology, diagnosis, treatment and prevention of cancer.

As the only National Cancer Institute-designated cancer center in Nebraska, the Fred & Pamela Buffett Cancer Center provides the best in science and clinical practice. Today, more than 200 oncologists and basic scientists are working together to find better ways to diagnose, treat and prevent cancer.

Clinical care is provided to patients at multiple sites across the Omaha-metro area and into southwest Iowa—the regions for which the Nebraska Medicine Cancer Network serves. 


Considered to be a Center of Excellence for the study of lymphoma, much emphasis is placed on integrated laboratory and clinical research in this disease. The Center's Lymphoma Study Group has reviewed more than 40,000 biopsies and created a clinical outcome database to correlate the findings. Nebraska Medicine’s stem cell transplantation program has been ranked as one of the busiest adult and pediatric stem cell transplantation programs in the world. The program, which was established in 1983, has been recognized internationally for pioneering autologous transplantation for lymphoma, using peripheral stem cells as an alternative rescue product; conducting groundbreaking transplant studies; and performing transplants in alternate settings other than traditional inpatient hospital units. More recently, CAR T-cell therapy is now available at Nebraska Medicine.

Stem Cell Transplant Program:
The diseases most treated using stem cell transplantation are non-Hodgkin lymphoma, Hodgkin lymphoma, leukemia, multiple myeloma and solid tumors (including breast cancer or testicular cancer). Various other hematological and non-hematological diseases are treated on a case-by-case basis. Autologous, related and unrelated myeloablative allogeneic, related and unrelated non-myeloablative, and cord blood transplants are provided for adults and children. The program is accredited by the Foundation for the Accreditation of Cellular Therapy (FACT).

Pancreatic Cancer
The Fred & Pamela Buffett Cancer Center has a $5.3 million National Cancer Institute Specialized Program of Research Excellence (SPORE) grant in pancreatic cancer. SPORE offers large, multidisciplinary federal grants that fund scientific research aimed at bringing new laboratory findings quickly to the clinic. In partnership, our doctors have access to the latest pancreatic treatments and therapies in clinical trials.

Breast Cancer
Our breast cancer program use current treatments and advanced therapies including clinical trials to improve the outcomes for many breast cancer patients. Genetic testing and advanced reconstructive surgery are also an integral part of the treatment plan. All to offer our patients unique options based on personal preferences.

Radiation Oncology
Nebraska Medicine offers radiation therapy as a highly effective and targeted cancer therapy used in 70 percent of all cancer patients. Revolutionary advances in the field of Radiation Oncology have been made over the past 10-15 years. More precise and targeted therapy delivery and improvements in imaging help physicians spare normal tissues to a greater degree than in past years. Radiation therapy is often used in conjunction with other treatment modalities, such as surgery or chemotherapy, or can be used as the sole treatment modality.

Surgical Oncology
Nebraska Medicine has a robust surgical oncology program offering patients unique treatment options not available elsewhere in the region. The program offers a comprehensive approach to cancer care with the largest number of fellowship-trained surgical oncologists in the Midwest. Several areas of surgical therapies are available including breast, gastrointestinal, urologic, thoracic, gynecologic, lung, thyroid and neuro-oncology.


Research at the Buffett Cancer Center is conducted in four research programs: 
1. Cancer genes and molecular regulation
2. Molecular biochemical etiology
3. Gastrointestinal cancer
4. Prevention and control

Other notable programs in research include the center’s work on lymphoma and bone marrow transplantation, pancreatic cancer and breast cancer.


  • National Cancer Institute (NCI) Designation
    • This designation recognizes the Fred & Pamela Buffett Cancer Center offers patients options for prevention, diagnosis and treatment and access to clinical trials not available elsewhere.
  • National Comprehensive Cancer Network
    • The National Comprehensive Cancer Network (NCCN) is an alliance of the world’s leading cancer centers, working together to develop national treatment guidelines for cancers based on the latest research. The Fred & Pamela Buffett Cancer Center is one of the founding members.
  • American College of Surgeons Commission on Cancer
    • This accreditation ensures patients receive comprehensive, state-of-the-art services provided by a multi-specialty team coordinating all aspects of cancer care.
  • Foundation for the Accreditation of Cellular Therapy (FACT)
    • The FACT accreditation demonstrates our commitment to quality in cellular therapy and blood and marrow transplantation and ensures our transplant program meets rigorous international standards.
  • Oncology Certified Nurses
    • Oncology Certified Nurses (OCN) working at Nebraska Medicine obtain certification in Oncology Nursing.
  • Magnet Status
    • Magnet Status is awarded by the American Nurses Credentialing Center (ANCC) and is the highest level of recognition for excellence in nursing practice.