National Comprehensive Cancer Network

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NCCN Guidelines and Compendium Updated

Flash Update Sent August 15, 2011

NCCN has published updates to the NCCN Guidelines and the NCCN Drugs & Biologics Compendium (NCCN Compendium®) for Cervical Cancer. These NCCN Guidelines are currently available as Version 1.2012.


  • “Cervical/vaginal cytology every 3-6 mo for 2 y, then every 6 mo for 3-5 y, then annually...” changed to “...every 6-12 mo for 3-5 y...”
  • “Chest x-ray annually (optional)” changed to “Chest x-ray annually for 5 y.

Principles of Radiation Therapy

Under External-Beam Radiation Therapy (EBRT), a fourth bullet regarding IMRT was added that states, “Intensity-modulated radiation therapy (IMRT) and similar highly conformal methods of dose delivery may be helpful in minimizing the dose to the bowel and other critical structures in the post-hysterectomy setting and in treating the para-aortic nodes when this is necessary. These techniques can also be useful when high doses are required to treat gross disease in regional lymph nodes. However, conformal external beam therapies (such as IMRT) should not be used as routine alternatives to brachytherapy for treatment of central disease in patients with an intact cervix. Very careful attention to detail and reproducibility (including consideration of target and normal tissue definitions, patient and internal organ motion, soft tissue deformation, and rigorous dosimetric and physics quality assurance) is required for proper delivery of IMRT and related highly conformal technologies.”

For the complete updated version of these and all NCCN Guidelines, visit