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NCCN Flash Update: NCCN Guidelines® & NCCN Compendium® Updated

NCCN has published updates to the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Older Adult Oncology. These NCCN Guidelines® are currently available as Version 2.2016.

  • Disease-Specific Issues Related to Age/Central Nervous System Cancers: (OAO-B 8 of 32)
    • The recommendations for adjuvant therapy for newly diagnosed patients with glioblastoma multiforme (GBM) were revised as follows based on the recent report from a global randomized phase III clinical trial.
      • Hypofractionated accelerated course RT with concurrent and adjuvant temozolomide is safe in older patients, and may have comparable survival and less toxicity to standard fractionated RT with concurrent and adjuvant temozolomide. Hypofractionated accelerated course RT with concurrent and adjuvant temozolomide has been shown to be superior to hypofractionated accelerated course of RT alone in a randomized controlled trial of newly diagnosed GBM patients 65 years of age.

*For your reference, the previous update (Version 1.2016) to the NCCN Guidelines for Older Adult Oncology, published on January 29, 2016, is available at the following link:


NCCN has published updates to the NCCN Drugs & Biologics Compendium (NCCN Compendium®) to reflect updates to the 2016 Version of the corresponding NCCN Guidelines:

  • Ovarian Cancer, Version 1.2016


For the complete updated versions of the NCCN Guidelines, NCCN Guidelines with NCCN Evidence Blocks™, the NCCN Compendium®, the NCCN Chemotherapy Order Templates (NCCN Templates®), and the NCCN Imaging Appropriate Use Criteria (NCCN Imaging AUC™), please visit

To access the NCCN Biomarkers Compendium™, please visit

To view the NCCN Guidelines for Patients®, please visit

Free NCCN Guidelines apps for iPhone, iPad, and Android tablets are now available! Visit

About NCCN Flash Updates™ 
NCCN Flash Updates™ is a subscription service from NCCN that provides timely notification of updated and new information appearing in the NCCN Guidelines, the NCCN Compendium, and other NCCN Content. 

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