National Comprehensive Cancer Network

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NCCN Biomarkers Compendium Now Available

NCCN announces the availability of the NCCN Biomarkers Compendium™–a tool developed to identify the appropriate use of biomarkers to screen, diagnose, monitor, and provide predictive and prognostic information for the treatment of patients.

FORT WASHINGTON, PA – The National Comprehensive Cancer Network® (NCCN®) today announces the availability of the NCCN Biomarkers Compendium™, a tool developed to identify how biomarkers are appropriately used to screen, diagnose, monitor, and provide predictive or prognostic information to ensure, ultimately, that patients with cancer have access to appropriate testing.

The tests included in the NCCN Biomarkers Compendium™ are those recommended in the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®)–the recognized standard for clinical policy in oncology and the most comprehensive and frequently updated guidelines available in any area of medicine.

Biomarker testing provides critical information needed to make certain that patients receive those treatments most likely to be effective, while avoiding possibly ineffective treatment and unnecessary side effects–an important component of personalized cancer treatment.

An accurate diagnosis is the cornerstone for the treatment of cancer; however, in this emerging era of highly targeted therapy, the correct diagnosis needs to be supplemented by critical information regarding tumor biomarkers, said Andrew D. Zelenetz, MD, PhD, Vice Chair of Medical Informatics, Department of Medicine at Memorial Sloan-Kettering Cancer Center and Chair of the NCCN Guidelines Panel for Non-Hodgkin’s Lymphoma. The NCCN Biomarkers Compendium will help clinicians select the appropriate tests that have been identified as clinically useful in the NCCN Guidelines.

The goal of the NCCN Biomarkers Compendium™ is to provide essential details for those biomarker uses which have been evaluated by NCCN Guidelines Panels and are recommended in the NCCN Guidelines®. Tests that measure changes in genes or gene products and which are used for diagnosis, screening, monitoring, surveillance, or for providing predictive or prognostic information are included in the Biomarkers Compendium™.

General information on appropriate methodologies for biomarker testing is provided, focusing on the biology or abnormality being measured rather than on commercially available tests or test kits. NCCN anticipates that this compendium may eventually be used by payers in much the same way the NCCN Drugs & Biologics Compendium (NCCN Compendium®) is utilized as a reference for coverage decisions.

NCCN is pleased to announce the availability of the NCCN Biomarkers Compendium, said Patricia J. Goldsmith, Executive Vice President and Chief Operating Officer. Together with the NCCN Compendium, this tool will indeed assist physicians and payors in identifying appropriate molecular testing from treatment and coverage perspectives and help them to provide the most up-to-date standard of care, based on NCCN Guidelines.

Currently, the NCCN Biomarkers Compendium™ includes more than 900 biomarker uses covering all NCCN Guidelines® disease sites where biomarker testing is applicable.

Users can visit today and enter the code: BIOMARKERS for 30 days of free access to the NCCN Biomarkers Compendium. Trial subscriptions are available through January 2013.

About the National Comprehensive Cancer Network

The National Comprehensive Cancer Network® (NCCN®), a not-for-profit alliance of 27 leading cancer centers, is dedicated to improving the quality and effectiveness of care provided to patients with cancer. Through the leadership and expertise of clinical professionals at NCCN Member Institutions, NCCN develops resources that present valuable information to the numerous stakeholders in the health care delivery system. As the arbiter of high-quality cancer care, NCCN promotes the importance of continuous quality improvement and recognizes the significance of creating clinical practice guidelines appropriate for use by patients, clinicians, and other health care decision-makers. The primary goal of all NCCN initiatives is to improve the quality, effectiveness, and efficiency of oncology practice so patients can live better lives. For more information, visit

The NCCN Member Institutions are:

  • Fred & Pamela Buffett Cancer Center
  • Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute
  • City of Hope Comprehensive Cancer Center
  • Dana-Farber/Brigham and Women's Cancer Center | Massachusetts General Hospital Cancer Center
  • Duke Cancer Institute
  • Fox Chase Cancer Center
  • Huntsman Cancer Institute at the University of Utah
  • Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance
  • The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
  • Robert H. Lurie Comprehensive Cancer Center of Northwestern University
  • Mayo Clinic Cancer Center
  • Memorial Sloan Kettering Cancer Center
  • Moffitt Cancer Center
  • The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute
  • Roswell Park Comprehensive Cancer Center
  • Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine
  • St. Jude Children's Research Hospital/The University of Tennessee Health Science Center
  • Stanford Cancer Institute
  • University of Alabama at Birmingham Comprehensive Cancer Center
  • UC San Diego Moores Cancer Center
  • UCSF Helen Diller Family Comprehensive Cancer Center
  • University of Colorado Cancer Center
  • University of Michigan Rogel Cancer Center
  • The University of Texas MD Anderson Cancer Center
  • University of Wisconsin Carbone Cancer Center
  • Vanderbilt-Ingram Cancer Center
  • Yale Cancer Center/Smilow Cancer Hospital