National Comprehensive Cancer Network



About NCCN

NCCN Offers HER2 Testing for Breast Cancer Patients™

Summary based on NCCN HER2 Testing Task Force Report

JENKINTOWN, Pa., January 8, 2007 — The National Comprehensive Cancer Network (NCCN) and Research Advocacy Network have created an online report to educate breast cancer patients about the significance and importance of HER2 testing. Results of this test are essential in determining the correct treatment plan for breast cancer patients.

Breast cancers can be categorized as HER2 positive or HER2 negative. HER2-positive breast cancer grows more quickly and is considered more aggressive. While studies indicate that trastuzumab (Herceptin®, Genentech) is effective in the treatment of HER2-positive early stage breast cancer and HER2-positive metastatic breast cancer, the drug is not effective in the treatment of HER2-negative breast cancers. As a result, it is important to have tests that accurately determine HER2 tumor status.

The NCCN HER2 Testing Report explains the different types of tests used to determine HER2 status. Patients learn the steps involved in each test and what the results signify. The Report also includes a list of frequently asked patient questions about HER2 testing. The clinical recommendations contained in the Fact Sheet are based on the findings of an expert task force convened by NCCN comprised of more than 20 world-renowned physicians.

The NCCN HER2 Testing Report is available on www.nccn.org.

About the National Comprehensive Cancer Network

The National Comprehensive Cancer Network® (NCCN®), a not-for-profit alliance of 27 of the world's leading cancer centers, is dedicated to improving the quality and effectiveness of care provided to patients with cancer. Through the leadership and expertise of clinical professionals at NCCN Member Institutions, NCCN develops resources that present valuable information to the numerous stakeholders in the health care delivery system. As the arbiter of high-quality cancer care, NCCN promotes the importance of continuous quality improvement and recognizes the significance of creating clinical practice guidelines appropriate for use by patients, clinicians, and other health care decision-makers. The primary goal of all NCCN initiatives is to improve the quality, effectiveness, and efficiency of oncology practice so patients can live better lives. For more information, visit NCCN.org.

The NCCN Member Institutions are:

  • Fred & Pamela Buffett Cancer Center
  • Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute
  • City of Hope Comprehensive Cancer Center
  • Dana-Farber/Brigham and Women's Cancer Center | Massachusetts General Hospital Cancer Center
  • Duke Cancer Institute
  • Fox Chase Cancer Center
  • Huntsman Cancer Institute at the University of Utah
  • Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance
  • The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
  • Robert H. Lurie Comprehensive Cancer Center of Northwestern University
  • Mayo Clinic Cancer Center
  • Memorial Sloan Kettering Cancer Center
  • Moffitt Cancer Center
  • The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute
  • Roswell Park Cancer Institute
  • Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine
  • St. Jude Children's Research Hospital/The University of Tennessee Health Science Center
  • Stanford Cancer Institute
  • University of Alabama at Birmingham Comprehensive Cancer Center
  • UC San Diego Moores Cancer Center
  • UCSF Helen Diller Family Comprehensive Cancer Center
  • University of Colorado Cancer Center
  • University of Michigan Comprehensive Cancer Center
  • The University of Texas MD Anderson Cancer Center
  • University of Wisconsin Carbone Cancer Center
  • Vanderbilt-Ingram Cancer Center
  • Yale Cancer Center/Smilow Cancer Hospital