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NCCN Offers HER2 Testing for Breast Cancer Patients™

Summary based on NCCN HER2 Testing Task Force Report

JENKINTOWN, Pa., January 8, 2007 — The National Comprehensive Cancer Network (NCCN) and Research Advocacy Network have created an online report to educate breast cancer patients about the significance and importance of HER2 testing. Results of this test are essential in determining the correct treatment plan for breast cancer patients.

Breast cancers can be categorized as HER2 positive or HER2 negative. HER2-positive breast cancer grows more quickly and is considered more aggressive. While studies indicate that trastuzumab (Herceptin®, Genentech) is effective in the treatment of HER2-positive early stage breast cancer and HER2-positive metastatic breast cancer, the drug is not effective in the treatment of HER2-negative breast cancers. As a result, it is important to have tests that accurately determine HER2 tumor status.

The NCCN HER2 Testing Report explains the different types of tests used to determine HER2 status. Patients learn the steps involved in each test and what the results signify. The Report also includes a list of frequently asked patient questions about HER2 testing. The clinical recommendations contained in the Fact Sheet are based on the findings of an expert task force convened by NCCN comprised of more than 20 world-renowned physicians.

The NCCN HER2 Testing Report is available on www.nccn.org.