NCCN Flash Updates: NCCN Guidelines^® and NCCN Compendium^® Updated for Non-Small Cell Lung Cancer

NCCN has published updates to the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines^®) and the NCCN Drugs and Biologics Compendium (NCCN Compendium^®) for Non-Small Cell Lung Cancer (NSCLC). These NCCN Guidelines^® are currently available as Version 5.2020.

• Advanced or Metastatic Disease
  • PD-L1 Expression Positive (≥50%) and EGFR, ALK, ROS1, BRAF, MET exon 14 skipping mutation, and RET negative and no contraindications to PD-1 or PD-L1 inhibitors (NSCL-30)
    • Atezolizumab added as a preferred first-line treatment option (category 2A).
  • Targeted Therapy or Immunotherapy for Advanced or Metastatic Disease (NSCL-I 1 of 2 and NSCL-I 2 of 2)
    • PD-L1 ≥50%: Atezolizumab added with reference.
• The discussion section has been updated to reflect the changes in the algorithm (MS-1).

For the complete updated versions of the NCCN Guidelines, NCCN Guidelines with NCCN Evidence Blocks™, the NCCN Drugs & Biologics Compendium (NCCN Compendium^®), the NCCN Biomarkers Compendium^®, the NCCN Chemotherapy Order Templates (NCCN Templates^®), the NCCN Radiation Therapy Compendium™, and the NCCN Imaging Appropriate Use Criteria (NCCN Imaging AUC™), please visit NCCN.org.

To view the NCCN Guidelines for Patients^®, please visit NCCN.org/patientguidelines.

Free NCCN Guidelines apps for iPhone, iPad, and Android devices are now available! Visit NCCN.org/apps.

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