NCCN Flash Updates: NCCN Guidelines and NCCN Templates Updated for B-Cell Lymphomas

NCCN has published updates to the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines^®) and the NCCN Drugs and Biologics Compendium (NCCN Compendium^®) for B-Cell Lymphomas. These NCCN Guidelines^® are currently available as Version 3.2022.

FOLL-B 3 of 5

• Third-Line and Subsequent Therapy and Third-Line and Subsequent Therapy for Elderly or Infirm
  • Umbralisib was removed as an option based on the voluntary withdrawal of the FDA indication.

MZL-A 2 of 4

• Second-Line and Subsequent Therapy and Second-Line and Subsequent Therapy for Elderly or Infirm
  • Umbralisib was removed as an option based on the voluntary withdrawal of the FDA indication.

Special Considerations for the Use of Small-Molecule Inhibitors

• Umbralisib removed

Previous updates to the NCCN Guidelines for B-Cell Lymphomas can be found in the UPDATES section of the current version.

NCCN has published updates to the NCCN Chemotherapy Order Templates (NCCN Templates^®) for B-cell Lymphomas to reflect the currently published NCCN Guidelines for B-Cell Lymphomas v3.2022

• The following NCCN template for Follicular Lymphoma has been DELETED:
  • FOL33: Umbralisib
• The following NCCN template for Gastric MALT Lymphoma has been DELETED:
  • GMALT24: Umbralisib
• The following NCCN template for Non-gastric MALT Lymphoma has been DELETED:
  • NGMALT23: Umbralisib
• The following NCCN template for Nodal Marginal Zone Lymphoma has been DELETED:
  • NMZL20: Umbralisib
• The following NCCN template for Splenic Marginal Zone Lymphoma has been DELETED:
  • SPLN23: Umbralisib

For the complete updated versions of the NCCN Guidelines, NCCN Guidelines with NCCN Evidence Blocks™, the NCCN Drugs & Biologics Compendium (NCCN Compendium^®), the NCCN Biomarkers Compendium^®, the NCCN Chemotherapy Order Templates (NCCN Templates^®), the NCCN Radiation Therapy Compendium™, and the NCCN Imaging Appropriate Use Criteria (NCCN Imaging AUC™), please visit NCCN.org.

To view the NCCN Guidelines for Patients^®, please visit NCCN.org/patientguidelines.

Free NCCN Guidelines apps for iPhone, iPad, and Android devices are now available! Visit NCCN.org/apps.

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