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NCCN Guidelines for Patients



Acute Lymphoblastic Leukemia, Version 1.2017


Cancer treatments

Supportive care

Tumor lysis syndrome







yndrome) is a rare condition that

occurs when many cancer cells die very quickly

due to cancer or its treatment. Chemotherapy may

destroy large numbers of leukemia cells quickly.

As the cells die, they break down and release their

contents into the blood. This changes the normal

balance of chemicals in the blood. It can cause very

high levels of certain chemicals.

Uric acid is one of the chemicals released by dying

cancer cells. Very high levels of uric acid and other

chemicals can be very bad for the body. It can cause

severe damage to organs such as the kidneys and

heart. Drugs such as allopurinol and rasburicase may

be given to prevent or lessen the effects of TLS.

Complementary and

alternative medicine



omplementary and




edicine) is a group of treatments

sometimes used by people with cancer.

Many CAMs are being studied to see if they

are truly helpful.



Complementary medicines are meant to

be used alongside standard therapies,

most often for relaxation, improving

your health, or to prevent or reduce side




Alternative medicine is treatment

or techniques that are used instead

of standard treatments such as

chemotherapy or radiation. Some are

sold as cures even though they haven’t

been proven to work in clinical trials.

Many cancer centers or local hospitals

have complementary therapy programs that

offer acupuncture, yoga, and other types of


It’s important to tell your treatment team if

you are using any complementary medicine,

especially supplements, vitamins, or herbs.

Some of these things can interfere with your

cancer treatment. For more information

about CAM, ask your doctor and visit the

websites in Part 6.