NCCN Guidelines for Patients
Acute Lymphoblastic Leukemia, Version 1.2017
Tumor lysis syndrome
yndrome) is a rare condition that
occurs when many cancer cells die very quickly
due to cancer or its treatment. Chemotherapy may
destroy large numbers of leukemia cells quickly.
As the cells die, they break down and release their
contents into the blood. This changes the normal
balance of chemicals in the blood. It can cause very
high levels of certain chemicals.
Uric acid is one of the chemicals released by dying
cancer cells. Very high levels of uric acid and other
chemicals can be very bad for the body. It can cause
severe damage to organs such as the kidneys and
heart. Drugs such as allopurinol and rasburicase may
be given to prevent or lessen the effects of TLS.
edicine) is a group of treatments
sometimes used by people with cancer.
Many CAMs are being studied to see if they
are truly helpful.
Complementary medicines are meant to
be used alongside standard therapies,
most often for relaxation, improving
your health, or to prevent or reduce side
Alternative medicine is treatment
or techniques that are used instead
of standard treatments such as
chemotherapy or radiation. Some are
sold as cures even though they haven’t
been proven to work in clinical trials.
Many cancer centers or local hospitals
have complementary therapy programs that
offer acupuncture, yoga, and other types of
It’s important to tell your treatment team if
you are using any complementary medicine,
especially supplements, vitamins, or herbs.
Some of these things can interfere with your
cancer treatment. For more information
about CAM, ask your doctor and visit the
websites in Part 6.