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NCCN Guidelines for Patients



Acute Lymphoblastic Leukemia, Version 1.2017


Treatment guide

Treatment guide

Part 5 is a guide through the treatment

options for patients with ALL. However,

these treatments may also be used for

patients with lymphoblastic lymphoma.

This information is taken from the treatment

guidelines written by NCCN experts of ALL. These

treatment guidelines list options for people with ALL

in general. Your doctors may suggest other treatment

for you based on your health and personal needs.

Discuss and decide on your treatment options with

your doctor.

NCCN experts recommend that all patients

receive treatment in a specialized cancer center

with expertise and experience in ALL.


treatment of ALL is very complex. It’s important to

be cared for by a multidisciplinary team of experts

with experience in treating patients your age. Access

to clinical trials is also a chief priority. Specialized

cancer centers, such as large academic centers,

have the experts, experience, and research to

provide the best care for patients with ALL.

Treatment options

There are multiple treatment options for ALL.

Treatment options that are best for you depend on a

number of factors. This includes the features of the

cancer, such as the cytogenetic subtype, as well as

your age and health status.

The treatment options in Part 5 are grouped by

patient age and presence of the Philadelphia

chromosome. The type and intensity of treatment

differs based on your age and health. To plan

treatment, doctors put patients into two main age


The AYA group includes patients who are 15 to 39

years of age. The older adult group includes patients

who are 40 years of age or older. The other main

factors that affect treatment planning and options are

described in Part 3 on page 26.