NCCN Guidelines for Patients
Acute Lymphoblastic Leukemia, Version 1.2017
A procedure in which a thin needle is inserted between the
bones of the spine to remove a sample of spinal fluid or give
drugs into the spinal fluid.
A small group of disease-fighting cells.
A network of organs and tissues in the body that collects
and transports a fluid (lymph) and fights germs. This system
includes the bone marrow, lymph nodes, lymph vessels,
thymus, and spleen.
An immature cell that becomes a mature white blood cell
called a lymphocyte.
A fast-growing cancer that starts in the lymphatic system
and causes too many lymphoblasts to build up in lymph
nodes or other parts of the lymph system.
A type of white blood cell that helps protect the body from
infection and disease.
magnetic resonance imaging (MRI) scan
A test that uses radio waves and powerful magnets to make
pictures of the inside of the body.
The third round (phase) of treatment that is given to keep up
(maintain) good treatment results.
A tool that uses lenses to see things the eyes can’t.
minimal residual disease (MRD)
A very small amount of cancer cells left in the body after
treatment that can’t be seen with a microscope.
A type of immune system protein that is made in a lab and
can attach to a certain target, such as a substance on the
surface of cancer cells.
The use of two or more cancer drugs.
Includes many doctors and other health care professionals
who are experts in different areas of cancer care.
An abnormal change.
A doctor who’s an expert in testing cells and tissue to find
Based on treatment designed for or given to children.
A detailed plan of a medical treatment for children.
A treatment plan that specifies the drug(s), dose, and
schedule for a course of treatment designed for or given to
An abnormal, short chromosome 22 that is formed when
parts of chromosomes 9 and 22 switch with each other. Also
called Ph chromosome.
The leukemia cells do not contain the abnormal Philadelphia
The leukemia cells contain the abnormal Philadelphia
A review of the body by a health expert for signs of disease.
A type of blood cell that helps control bleeding.
polymerase chain reaction (PCR)
A sensitive lab test that is used to look for abnormal
changes in a cell’s genes (coded instructions for controlling
cells) and chromosomes (long strands of genes).
poor risk feature
Something linked with a higher chance (risk) that cancer will
come back after treatment.
positron emission tomography (PET) scan
A test that uses radioactive material to take pictures of the
inside of the body.
Treatment given after all signs and symptoms of cancer
have disappeared (called a remission) following initial