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NCCN Guidelines for Patients



Acute Lymphoblastic Leukemia, Version 1.2017



The likely or expected course, pattern, and outcome of a

disease based on tests.

prognostic factor

Something that affects and helps predict the likely outcome

of a disease.


A detailed plan of a medical study, treatment, or procedure.

radiation therapy

Use of high-energy rays to destroy cancer cells.

red blood cell

A type of blood cell that carries oxygen from the lungs to the

rest of the body.


Disease that does not improve or go away in response to



A treatment plan that specifies the drug(s), dose, and

schedule for a course of treatment.


The return of leukemia cells after a period of improvement.


The signs and symptoms of cancer have disappeared as a

result of treatment.

remission induction

The first round (phase) of treatment that is given to rid the

body of leukemia cells and make all signs and symptoms

of the cancer disappear. Also called induction or induction



A drug that helps a person to relax or go to sleep.

side effect

An unhealthy or unpleasant physical or emotional response

to treatment.

spinal cord

The bundle of nerves that runs from the base of the skull

down the back and carries messages between the brain and

other parts of the body.

spinal fluid

The fluid that surrounds the brain and spinal cord. Also

called cerebrospinal fluid.


An organ to the left of the stomach that helps protect the

body from disease.

stem cell transplant (SCT)

Treatment that replaces damaged or diseased cells in the

bone marrow—soft tissue in the center of bones where

blood cells are made—with healthy blood-forming cells

called blood stem cells.


A drug used to reduce redness, swelling, and pain, but also

to kill leukemia cells. Also called corticosteroid.


Smaller groups that a type of cancer is divided into based

on certain features of the cancer cells.

supportive care

Treatment for the symptoms or health conditions caused by

cancer or cancer treatment.


A new or changed health problem a person experiences that

may indicate a disease.

targeted therapy

Treatment with drugs that target a specific or unique feature

of cancer cells.


One of two main types of white blood cells called

lymphocytes that help protect the body from infection and

disease. Also called T-lymphocyte.

T-cell ALL

A fast-growing (acute) blood cancer (leukemia) that starts in

a T-lymphoblast—an immature cell that normally becomes a

mature white blood cell called a T-cell or T-lymphocyte.


Two egg-shaped glands found inside the sac between the

legs of a man.


A small organ in the upper, front part of the chest that is part

of the body’s disease-fighting system.


One of two main types of white blood cells called

lymphocytes that help protect the body from infection and

disease. Also called T-cell.