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NCCN Guidelines for Patients



Acute Lymphoblastic Leukemia, Version 1.2017



Replacing lost blood with new blood.


When pieces of two chromosomes (long strands of coded

instructions for controlling cells) break off and switch with

each other.

treatment response

An outcome or improvement related to treatment.

tumor lysis syndrome (TLS)

A condition that occurs when many cancer cells die very

quickly and release their contents into the blood, which can

damage the kidneys and other organs.

tumor lysis syndrome (TLS) panel

A test that measures certain chemicals that are released

into the blood when cancer cells die.

tyrosine kinase inhibitor (TKI)

A type of drug that targets and blocks the protein made

by the


gene so that it can’t tell leukemia cells to


U.S. Food and Drug Administration (FDA)

A federal government agency that regulates drugs and food.

uric acid

A chemical that is made and released into the blood when

cells and other substances in the body break down.


A biological agent inserted into the body to prevent a



A small tube that carries blood to the heart from anywhere in

the body.

white blood cell

A type of blood cell that helps fight infections in the body.