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NCCN Guidelines for Patients


Adolescents and Young Adults with Cancer, Version 1.2017

Learn about treatment options.

Part 5 goes over clinical trials for cancer

treatment and commonly used treatments

that may be offered to you. You can also

get the facts about complementary and

alternative therapies.

If you had been diagnosed with cancer a decade ago,

your treatment options were less than they are today.

Thanks to technical advances and research on how

and why cancer develops, doctors can now prescribe

many therapies that target cancer with greater

accuracy than ever before. Understanding these

therapies can help you work with your treatment

team. You can make informed decisions about your

treatment plan.

What are clinical trials?

A clinical trial is a type of research study that people

chose to take part in. Clinical trials help learn how to

prevent, diagnose, and treat a disease like cancer.

Because of clinical trials, doctors find safe and helpful

ways to improve your cancer care. This guide has

many of those tests and treatments used to help

young people with cancer.

Clinical trials go through levels or phases of testing.

These phases help move the research along to find

out what works best for people with cancer.


Phase I looks at how much and how to give

the treatment.


Phase II tests for side effects and how it works

on the cancer type.


Phase III compares the treatment (or new use

of treatment) to what is commonly used.


Phase IV follows late side effects and if the

treatment still works after a long period of



Understanding your

treatment options

40 What are clinical trials?

41 What are local treatments?

43 What are systemic treatments?

45 How can I learn more about complementary and

alternative medicine (CAM)?

46 Review