Table of Contents Table of Contents
Previous Page  59 / 88 Next Page
Show Menu
Previous Page 59 / 88 Next Page
Page Background


NCCN Guidelines for Patients



Brain Cancer – Gliomas, Version 1.2016

receive a CT scan. Images will be made with and

without contrast.

After surgery, you may receive more treatment if

you are healthy enough. One option is to receive

chemotherapy. Another option is to receive radiation

therapy again. Radiation may work well if it’s been

a long time since your last radiation treatment or it

worked well before.

Supportive care aims to improve your quality of life.

It includes treatment for symptoms caused by the

cancer or prior treatment. It is an option if you can’t

have more cancer treatment after surgery. It is also

an option if the recurrence can’t be treated with


The cancer is widespread

Widespread cancer may be treated with

chemotherapy if you are healthy enough. A KPS

score of 60 or higher is a sign of good health.

Surgery may also be an option for large tumors

causing symptoms. If your KPS score is 59 or less,

you may receive supportive care to improve your

quality of life.




Surgery is often used to confirm the

diagnosis and treat oligodendrogliomas and

oligoastrocytomas. Molecular testing is also

important for diagnosis and treatment planning.

If the cancer is grade III, carmustine wafers

placed into your brain during surgery may be

an option. MRI is needed after major surgery to

assess how much of the cancer was removed.



More treatment is often received after surgery.

Only some grade II cancers may be observed

rather than treated. Treatment may consist

of radiation therapy, chemotherapy, or both.

Radiation with chemotherapy is the most

proven treatment for grade III anaplastic

oligodendrogliomas with 1p19q co-deletion.



MRI scans are needed on a regular basis to

track treatment results.



If a low-grade oligodendroglioma and

oligoastrocytoma returns, surgery may be

an option. Treatment after surgery depends

on your treatment history. You may receive

radiation, chemotherapy, or both. Likewise,

radiation, chemotherapy, or both may be

received if surgery isn’t an option.



If a high-grade oligodendroglioma and

oligoastrocytoma returns, treatment options

depend on where the cancer is and its

extent. Surgery may be an option followed

by chemotherapy or radiation. When surgical

treatment isn’t an option, other options include

chemotherapy, surgery for symptoms, and

supportive care.


Oligodendrogliomas and oligoastrocytomas Review