NCCN Guidelines for Patients
Brain Cancer – Gliomas, Version 1.2016
receive a CT scan. Images will be made with and
After surgery, you may receive more treatment if
you are healthy enough. One option is to receive
chemotherapy. Another option is to receive radiation
therapy again. Radiation may work well if it’s been
a long time since your last radiation treatment or it
worked well before.
Supportive care aims to improve your quality of life.
It includes treatment for symptoms caused by the
cancer or prior treatment. It is an option if you can’t
have more cancer treatment after surgery. It is also
an option if the recurrence can’t be treated with
The cancer is widespread
Widespread cancer may be treated with
chemotherapy if you are healthy enough. A KPS
score of 60 or higher is a sign of good health.
Surgery may also be an option for large tumors
causing symptoms. If your KPS score is 59 or less,
you may receive supportive care to improve your
quality of life.
Surgery is often used to confirm the
diagnosis and treat oligodendrogliomas and
oligoastrocytomas. Molecular testing is also
important for diagnosis and treatment planning.
If the cancer is grade III, carmustine wafers
placed into your brain during surgery may be
an option. MRI is needed after major surgery to
assess how much of the cancer was removed.
More treatment is often received after surgery.
Only some grade II cancers may be observed
rather than treated. Treatment may consist
of radiation therapy, chemotherapy, or both.
Radiation with chemotherapy is the most
proven treatment for grade III anaplastic
oligodendrogliomas with 1p19q co-deletion.
MRI scans are needed on a regular basis to
track treatment results.
If a low-grade oligodendroglioma and
oligoastrocytoma returns, surgery may be
an option. Treatment after surgery depends
on your treatment history. You may receive
radiation, chemotherapy, or both. Likewise,
radiation, chemotherapy, or both may be
received if surgery isn’t an option.
If a high-grade oligodendroglioma and
oligoastrocytoma returns, treatment options
depend on where the cancer is and its
extent. Surgery may be an option followed
by chemotherapy or radiation. When surgical
treatment isn’t an option, other options include
chemotherapy, surgery for symptoms, and
Oligodendrogliomas and oligoastrocytomas Review