NCCN Guidelines for Patients® | Chronic Lymphocytic Leukemia
37 NCCN Guidelines for Patients ® : Chronic Lymphocytic Leukemia, 2018 4 Treatment guide Treatment options for CLL The second section is for younger and fairly healthy people. It starts on page 40. This section is for people who are younger than 65 years of age and are fairly healthy besides having cancer. The standard of care includes a purine analog. The next section is for people who are older or quite sick. It is for those who are: 1) 65 years of age and older; or 2) younger than 65 years but have serious health problems in addition to cancer. Some of the treatment options for this group include a purine analog. On page 45 you will read about Richter’s transformation (including DLBCL [ d iffuse l arge B -cell l ymphoma] and Hodgkin lymphoma) and CLL with progression. Some people with CLL can develop these cancers or the cancer itself can progress. The testing before treatment is similar to CLL workup but treatment options may differ for each cancer type. Lastly, you will learn about supportive care options. Supportive care is treatment given to relieve the health problems caused by cancer and side effects of cancer treatment. Managing symptoms and side effects with supportive care is important for your quality of life and treatment outcome.