NCCN Guidelines for Patients® | Chronic Lymphocytic Leukemia

40 NCCN Guidelines for Patients ® : Chronic Lymphocytic Leukemia, 2019 Words to know mantle cell lymphoma A cancer of B cells that have too many proteins called cyclin D1. MBL monoclonal B lymphocytosis medical history A report of all your health events and medications. monoclonal antibody A type of cancer drug that stops growth signals. monoclonal B lymphocytosis (MBL) A health condition that causes a high number of B cells. MRD minimal residual d isease MUGA multi-gated acquisition multigated acquisition (MUGA) scan A test that uses radiation to make pictures of the heart. observation A period of testing for changes in cancer status while not receiving treatment. pathologist A doctor who’s an expert in testing cells and tissue to find disease. performance status A rating of one’s ability to do daily activities. PET positron emission tomography physical exam A study of the body by a health expert for signs of disease. PI3K phosphoinositide 3-kinase delta positron emission tomography (PET) A test that uses radioactive material to see the shape and function of body parts. prognosis The likely course and outcome of a disease based on tests. pure red cell aplasia A health condition in which the number of young red blood cells is very low. purine analogs A drug that prevents the DNA “building blocks” labeled A and G from being used. Rai staging system A rating scale of the outlook of chronic lymphocytic leukemia. reticulocyte A young red blood cell that is formed in bone marrow and present briefly in blood. Richter’s transformation A change from a slow-growing leukemia into a fast-growing lymphoma. Also called Richter’s syndrome. side effect An unhealthy or unpleasant physical or emotional response to treatment. SLL small lymphocytic leukemia spleen An organ to the left of the stomach that helps protect the body from disease. steroid A drug used to reduce redness, swelling, and pain, but also to kill cancer cells. supportive care Health care that includes symptom relief but not cancer treatment. Also called palliative care. targeted therapy A drug treatment that impedes the growth process specific to cancer cells. tumor lysis syndrome (TLS) A health condition caused by the rapid death of many cancer cells by treatment. ultrasound A test that uses sound waves to take pictures of the inside of the body. Also called ultrasonography. uric acid A chemical that is made when cells and certain eaten food break down. vaccine A dead or weak germ that is inserted into the body to prevent a disease.