NCCN Guidelines for Patients® | Chronic Lymphocytic Leukemia

46 NCCN Guidelines for Patients ® : Chronic Lymphocytic Leukemia, 2018 If Richter’s transformation or CLL with progression, more tests will be done before treatment starts. The test results will help your doctor plan your next steps of care. See Guide 11 for a list of tests that must be done and some that may be done in certain cases. Guide 11. Care before treatment Must haves Type of care Sometimes useful Type of care • Medical history Medical history • Bone marrow aspiration + biopsy Bone and marrow test • Physical exam (including Waldeyer’s ring [tissue inside the throat] and size of the liver and spleen) Exam of the body • Echocardiogram or MUGA Heart test • Performance status Status of activity level • Hepatitis B testing Blood test • Complete blood count with differential Blood test • HLA typing Blood test • Comprehensive metabolic panel Blood test • Pregnancy test if you can have babies Pregnancy test • LDH Blood test • Uric acid Blood test • Check for the Epstein-Barr virus Blood test • Whole body PET/CT scan or CT scan of the chest, abdomen, and pelvis Imaging test 4 Treatment guide Richter’s transformation and CLL with progression

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