NCCN Guidelines for Patients® | Chronic Lymphocytic Leukemia

48 NCCN Guidelines for Patients ® : Chronic Lymphocytic Leukemia, 2018 4 Treatment guide Richter’s transformation and CLL with progression Guide 13 lists further options after chemotherapy is given for DLBCL. If the chemotherapy is working and you are healthy enough, your doctor may consider an allogeneic SCT. If chemotherapy is not working, your doctor may recommend a clinical trial. For further treatment details, it is also helpful to read the NCCN Guidelines for Patients ® : Diffuse Large B-Cell Lymphoma. These guidelines are available for free at . Guide 13. Further treatment for DLBCL Response to chemotherapy Treatment options Chemotherapy sensitive (chemotherapy is working) ª • Consider allogeneic SCT Chemotherapy refractory (chemotherapy is not working) ª • Clinical trial or • See NCCN Guidelines for B-Cell Lymphomas (treatment for DLBCL)