NCCN Guidelines for Patients® | Chronic Lymphocytic Leukemia

64 NCCN Guidelines for Patients ® : Chronic Lymphocytic Leukemia, 2018 Dictionary monoclonal antibody Man-made antibodies that attach proteins on cancer cells. monoclonal B-lymphocytosis (MBL) A health condition that features high numbers of B-cells but is not cancer. multi-gated acquisition (MUGA) scan A test of the heart that uses radiation to make pictures. natural killer (NK) cell One of three types of a white blood cell called a lymphocyte. observation A period of testing for changes in cancer status while not receiving a specific treatment. pathologist A doctor who’s an expert in testing cells to find disease. performance status A rating of one’s ability to do daily activities. physical exam A review of the body by a health expert for signs of disease. positron emission tomography (PET) A test that uses radioactive material to see the shape and function of body parts. prognosis The expected pattern and outcome of a disease based on tests. pure red cell aplasia Very low numbers of the precursor cells to red blood cells in bone marrow. purine analogs A type of chemotherapy that increases the likelihood of serious infections. Rai staging system The system used to stage chronic lymphocytic leukemia. reticulocytes Precursor cells to mature red blood cells. Richter’s transformation Cellular level transformation of chronic lymphocytic leukemia to diffuse large B-cell lymphoma or Hodgkin lymphoma. sedative A drug that helps a person to relax or go to sleep. side effect An unplanned physical or emotional response to treatment. spleen An organ to the left of the stomach that helps protect the body from disease. stem cell transplant A cancer treatment that destroys bone marrow then replaces it by adding healthy blood stem cells. steroid A drug used to reduce redness, swelling, and pain, but also to kill cancer cells. supportive care Treatment for the symptoms or health conditions caused by cancer or cancer treatment. targeted therapy Drugs that stop the growth process that is specific to cancer cells. T-cell One of three types of a white blood cell called a lymphocyte. thymus A gland located in the throat, just beneath the voice box. tonsil A group of tissue within the throat that contains many white blood cells called lymphocytes and fights germs that enter the mouth and nose. tumor lysis syndrome (TLS) A condition that occurs when many cancer cells die very quickly and release their contents into the blood, which can damage the kidneys and other organs. ultrasound A test that uses sound waves to take pictures of the inside of the body. uric acid A chemical that is made and released into the blood when cells and other substances in the body break down. vaccine A biological agent inserted into the body to prevent a disease.