NCCN Guidelines for Patients® | Chronic Lymphocytic Leukemia

Contents 7
How to use this book 8
1: Chronic lymphocytic leukemia 9
Lymphocytes 10
CLL basics 11
Review 15
2: Treatment planning 16
Medical history 17
Physical exam 17
Blood tests 19
Imaging tests 22
Bone and marrow test 23
Heart tests 24
Fertility and pregnancy 24
Starting treatment 25
Review 26
3: Overview of cancer treatments 27
Clinical trials 28
Chemotherapy 29
Steroids 31
Immunomodulators 31
Targeted therapy 32
Stem cell transplant 34
4: Treatment guide 37
Treatment options for CLL 38
Treatment for CLL without del(17p) or TP53 mutation 40
Treatment for CLL with del(17p) or TP53 mutation 46
Richter’s transformation and CLL with progression 47
Supportive Care 51
Review 54
5: Making treatment decisions 55
It’s your choice 56
Questions to ask your doctors 56
What’s my diagnosis and prognosis? 57
What are my options? 58
What does each option require of me? 59
What is your experience? 60
Deciding between options 61
Websites 62
Review 62
Glossary 63
Dictionary 64
Acronyms 67
NCCN Panel Members for Chronic Lymphocytic Leukemia 70
NCCN Member Institutions 71
Index 72

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